SCHEMBL2203418

SCHEMBL2203418

CO[Si](CCc1ccccc1C)(OC)OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.50
CHRM2 P08172 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
MAPT P10636 2/20 0.38
ALOX12 P18054 1/20 0.38
P2RX7 Q99572 1/20 0.37
TSHR P16473 1/20 0.37
LMNA P02545 2/20 0.37
POLB P06746 1/20 0.37
DAO P14920 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
ALOX5 P09917 1/20 0.36
HPGD P15428 3/20 0.36
ALDH1A1 P00352 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL139732 0.87 TAAR1 (0.42) TAAR1CHRM2MAPTCA12CA1
SCHEMBL30276868 0.87 TAAR1 (0.42) TAAR1CHRM2MAPTCA12CA1
SCHEMBL13027395 0.85 P2RX7 (0.37) TAAR1MEN1KMT2AMAPTALOX12
SCHEMBL13027421 0.83 SCN8A (0.36) TAAR1MEN1KMT2AMAPTTSHR
SCHEMBL2196104 0.82 TAAR1 (0.48) TAAR1CHRM2MEN1KMT2AMAPT
SCHEMBL13027385 0.82 TAAR1 (0.34) TAAR1MEN1KMT2AMAPTALOX12
SCHEMBL11651264 0.81 TAAR1 (0.47) TAAR1KMT2AP2RX7DAOCA12
SCHEMBL13027638 0.80 SCN8A (0.32) TAAR1MEN1KMT2AMAPTLMNA
SCHEMBL6332009 0.80 MTNR1A (0.41) TAAR1MAPTHPGDALDH1A1KDM4E
SCHEMBL1968082 0.80 TAAR1 (0.60) TAAR1CHRM2MAPTCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9688784-B2 Treated fillers, compositions containing same, and articles prepared therefrom PPG INDUSTRIES OHIO, INC. (US) 2017-06-27 US claimed
EP-1782436-B1 METHOD FOR TREATING ELECTRICAL CABLE AT SUSTAINED ELEVATED PRESSURE NOVINIUM INC (US) 2017-05-31 EP disclosed
EP-2121273-B1 ACID-CATALYZED DIELECTRIC ENHANCEMENT FLUID AND CABLE RESTORATION METHOD EMPLOYING SAME NOVINIUM INC (US) 2014-06-25 EP disclosed
US-8697330-B2 Composition for forming a silicon-containing antireflection film, substrate having the silicon-containing antireflection film from the composition and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-04-15 US disclosed
US-8656586-B2 Method for treating electrical cable at sustained elevated pressure NOVINIUM, INC. (US) 2014-02-25 US disclosed
EP-1744866-B1 METHOD FOR SELECTING FORMULATIONS TO TREAT ELECTRICAL CABLES NOVINIUM INC (US) 2012-08-08 EP disclosed
US-8205326-B2 Method for treating electrical cable at sustained elevated pressure NOVINIUM, INC. (US) 2012-06-26 US disclosed
US-20120102729-A1 METHOD FOR TREATING ELECTRICAL CABLE AT SUSTAINED ELEVATED PRESSURE NOVINIUM, INC. (US) 2012-05-03 US disclosed
US-7976747-B2 Method for restoring power cables NOVINIUM, INC. (US) 2011-07-12 US disclosed
US-20100285407-A1 Composition for forming a silicon-containing antireflection film, substrate having the silicon-containing antireflection film from the composition and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-11-11 US disclosed
US-20100095521-A1 METHOD FOR TREATING ELECTRICAL CABLE AT SUSTAINED ELEVATED PRESSURE NOVINIUM, INC. (US) 2010-04-22 US disclosed
US-7615247-B2 Promoting transport of dielectric enhancing fluid into polymeric insulation; utilizing residual injection pressure to expand interstitial void volume along entire length of treatment segment NOVINIUM, INC. (US) 2009-11-10 US disclosed
US-7611748-B2 Method for selecting formulations to treat electrical cables NOVINIUM, INC. (US) 2009-11-03 US disclosed
US-20090133799-A1 METHOD FOR RESTORING POWER CABLES NOVINIUM, LLC 2009-05-28 US disclosed
US-20080173467-A1 ACID-CATALYZED DIELECTRIC ENHANCEMENT FLUID AND CABLE RESTORATION METHOD EMPLOYING SAME NOVINIUM, INC. (US) 2008-07-24 US disclosed
US-20050192708-A1 Method for selecting formulations to treat electrical cables NOVINIUM, INC. (US) 2005-09-01 US disclosed
US-20050189130-A1 Method for treating electrical cable at sustained elevated pressure NOVINIUM, INC. (US) 2005-09-01 US disclosed
US-4769308-A Dry presensitized plate with photosensitive layer containing organotin FUJI PHOTO FILM CO., LTD. (JP) 1988-09-06 US disclosed
US-4099981-A MINERAL FILLER UNION CARBIDE CORPORATION (US) 1978-07-11 US disclosed
US-4044037-A COUPLING AGENTS UNION CARBIDE CORPORATION (US) 1977-08-23 US disclosed