SCHEMBL2203546

SCHEMBL2203546

NCCCc1cccc(OCCCCO)c1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.50
CYP4A11 Q02928 2/20 0.50
TAAR1 Q96RJ0 1/20 0.46
POLB P06746 1/20 0.44
PRSS1 P07477 6/20 0.44
KCNH2 Q12809 1/20 0.44
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
CYP2D6 P10635 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2205041 0.98 CYP4F2 (0.49) CYP4F2CYP4A11TAAR1POLBPRSS1
SCHEMBL29818925 0.98 CYP4F2 (0.49) CYP4F2CYP4A11TAAR1POLBPRSS1
SCHEMBL29818682 0.95 CYP4F2 (0.51) CYP4F2CYP4A11TAAR1POLBPRSS1
SCHEMBL2204526 0.95 CYP4F2 (0.51) CYP4F2CYP4A11TAAR1POLBPRSS1
SCHEMBL2206860 0.92 CYP4F2 (0.51) CYP4F2CYP4A11TAAR1POLBPRSS1
SCHEMBL611426 0.91 CYP4F2 (0.50) CYP4F2CYP4A11TAAR1POLBKCNH2
SCHEMBL612944 0.89 CYP4F2 (0.49) CYP4F2CYP4A11TAAR1PRSS1KCNH2
SCHEMBL611425 0.89 CYP4F2 (0.49) CYP4F2CYP4A11TAAR1PRSS1KCNH2
SCHEMBL610023 0.89 CYP4F2 (0.51) CYP4F2CYP4A11TAAR1POLBKCNH2
SCHEMBL2335254 0.88 CYP4F2 (0.50) CYP4F2CYP4A11TAAR1KCNH2PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029708-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2024-07-09 US disclosed
US-12029708-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2024-07-09 US disclosed
US-12029708-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2024-07-09 US disclosed
US-20230218549-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2023-07-13 US disclosed
US-20230218549-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2023-07-13 US disclosed
US-11446261-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2022-09-20 US disclosed
US-20210077427-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2021-03-18 US disclosed
US-20210077427-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2021-03-18 US disclosed
US-10639286-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2020-05-05 US disclosed
US-10639286-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2020-05-05 US disclosed
US-20120122938-A1 Alkoxy Compounds for Disease Treatment ACUCELA INC. (US) 2012-05-17 US disclosed
US-7982071-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2011-07-19 US disclosed
US-7982071-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2011-07-19 US disclosed
US-7982071-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2011-07-19 US disclosed
US-20090326074-A1 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2009-12-31 US disclosed
US-20090326074-A1 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2009-12-31 US disclosed
US-20090326074-A1 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2009-12-31 US disclosed
EP-2091955-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT Acucela, Inc. (US) 2009-08-26 EP disclosed
WO-2009045479-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. (US) 2009-04-09 WO disclosed
WO-2009045479-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. (US) 2009-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12029708-B2 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER CYP4F2 4298/4885CYP4A11 1129/4885TAAR1 1482/4885
US-20120122938-A1 Alkoxy Compounds for Disease Treatment ALDH1A2, CLN6, AGER CYP4F2 4298/4885CYP4A11 1129/4885TAAR1 1482/4885
US-20210077427-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER CYP4F2 4298/4885CYP4A11 1129/4885TAAR1 1482/4885
US-20230218549-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER CYP4F2 4314/4885CYP4A11 1054/4885TAAR1 1463/4885
US-11446261-B2 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER CYP4F2 4298/4885CYP4A11 1129/4885TAAR1 1482/4885
US-20090326074-A1 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER CYP4F2 4298/4885CYP4A11 1129/4885TAAR1 1482/4885
US-10639286-B2 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER CYP4F2 4298/4885CYP4A11 1129/4885TAAR1 1482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.