SCHEMBL2203572

SCHEMBL2203572

Nc1nc(N)nc(Nc2ccc(C=Cc3ccc(Nc4nc(N)nc(Nc5ccccc5)n4)cc3S(=O)(=O)O)c(S(=O)(=O)O)c2)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 2/20 0.46
▸ CA1 P00915 2/20 0.46
▸ CA2 P00918 2/20 0.46
▸ CA9 Q16790 2/20 0.46
▸ TERT O14746 1/20 0.43
▸ ENPP2 Q13822 1/20 0.43
▸ MAPT P10636 4/20 0.43
▸ APEX1 P27695 2/20 0.43
▸ NSD2 O96028 2/20 0.43
▸ CASP6 P55212 2/20 0.43
▸ KDM4E B2RXH2 2/20 0.43
▸ GAA P10253 2/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ POLB P06746 1/20 0.43
▸ APOBEC3A P31941 1/20 0.43
▸ RECQL P46063 1/20 0.43
▸ APOBEC3G Q9HC16 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ CDK9 P50750 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15783862 0.99 TERT (0.44) CA12CA1CA2CA9TERT
SCHEMBL2203103 0.99 TERT (0.44) CA12CA1CA2CA9TERT
SCHEMBL29970929 0.99 TERT (0.44) CA12CA1CA2CA9TERT
SCHEMBL8410087 0.98 CA12 (0.46) CA12CA1CA2CA9TERT
SCHEMBL8410062 0.98 TERT (0.43) CA12CA1CA2CA9TERT
Potassium SCHEMBL2219790 0.98 TERT (0.43) CA12CA1CA2CA9TERT
SCHEMBL15782099 0.94 CA12 (0.41) CA12CA1CA2CA9TERT
SCHEMBL16363762 0.94 CHAT (0.48) CA12CA1CA2CA9TERT
SCHEMBL17550065 0.93 CA12 (0.52) CA12CA1CA2CA9MAPT
SCHEMBL168451 0.93 ENPP2 (0.49) CA12CA1CA2CA9ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2716466-B1 THERMAL RECORDING MATERIAL CONTAINING STILBENE DISULPHONIC ACID FLUORESCENT WHITENING AGENT RICOH IND FRANCE SAS (FR) 2016-09-14 — — EP disclosed
EP-2722190-B1 Optimized undercoat for thermal recording material RICOH IND FRANCE SAS (FR) 2015-12-16 — — EP disclosed
EP-2722190-A1 Optimized undercoat for thermal recording material Ricoh Industrie France SAS (FR) 2014-04-23 — — EP disclosed
US-8546300-B2 Thermosensitive recording material and image recording method RICOH COMPANY, LTD. (JP) 2013-10-01 — — US disclosed
EP-2345541-B1 Thermosensitive recording material and image recording method RICOH CO LTD (JP) 2012-08-29 — — EP disclosed
US-20110177941-A1 THERMOSENSITIVE RECORDING MATERIAL AND IMAGE RECORDING METHOD RICOH COMPANY, LTD. (JP) 2011-07-21 — — US disclosed
EP-2345541-A2 Thermosensitive recording material and image recording method Ricoh Company, Ltd. (JP) 2011-07-20 — — EP disclosed
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