Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20656010 | 0.77 | GPR35 (0.40) | — | |
| SCHEMBL20656013 | 0.73 | GPR35 (0.41) | — | |
| SCHEMBL20656009 | 0.71 | DPP4 (0.46) | DPP4 | |
| SCHEMBL20655986 | 0.67 | DPP4 (0.47) | DPP4 | |
| SCHEMBL20656011 | 0.67 | GPR35 (0.38) | DPP4 | |
| SCHEMBL17112945 | 0.64 | GPR35 (0.41) | DPP4 | |
| SCHEMBL13407287 | 0.63 | DPP4 (0.47) | DPP4 | |
| SCHEMBL10550712 | 0.58 | DPP4 (0.41) | DPP4 | |
| SCHEMBL20656175 | 0.58 | GPR35 (0.32) | — | |
| SCHEMBL14686298 | 0.57 | DPP4 (0.44) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200165266-A1 | RING CLOSURE REACTION | FLEXENABLE LIMITED (GB) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165266-A1 | RING CLOSURE REACTION | LIG4, ATG7, RNF4 | DPP4 3055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.