Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22036717 | 0.92 | KDM4E (0.39) | KDM4EATML3MBTL1ALDH1A1HTT | |
| SCHEMBL22036139 | 0.90 | L3MBTL1 (0.43) | KDM4EATML3MBTL1ALDH1A1HTT | |
| SCHEMBL23760172 | 0.89 | L3MBTL1 (0.44) | KDM4EATML3MBTL1ALDH1A1HTT | |
| SCHEMBL22036326 | 0.89 | ATM (0.42) | KDM4EATML3MBTL1ALDH1A1HTT | |
| SCHEMBL22036701 | 0.88 | KDM4E (0.55) | KDM4EATML3MBTL1ALDH1A1HTT | |
| SCHEMBL22036135 | 0.86 | MEN1 (0.38) | KDM4EATML3MBTL1ALDH1A1PKM | |
| SCHEMBL22036321 | 0.85 | L3MBTL1 (0.46) | KDM4EATML3MBTL1ALDH1A1HTT | |
| SCHEMBL25480279 | 0.85 | ATM (0.42) | KDM4EATML3MBTL1ALDH1A1HTT | |
| SCHEMBL21578779 | 0.85 | ATM (0.46) | KDM4EATML3MBTL1ALDH1A1HTT | |
| SCHEMBL19359854 | 0.85 | ATM (0.46) | KDM4EATML3MBTL1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535619-B2 | Hexacyclic heteroaromatic compounds for electronic devices | MERCK PATENT GMBH (DE) | 2022-12-27 | — | — | US | disclosed |
| US-20200165252-A1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165252-A1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR ELECTRONIC DEVICES | ETV6, CYP2J2, CYP2D6 | KDM4E 2237/4885ATM 4482/4885L3MBTL1 3859/4885 |
| US-11535619-B2 | Hexacyclic heteroaromatic compounds for electronic devices | ETV6, CYP2J2, CYP2D6 | KDM4E 2237/4885ATM 4482/4885L3MBTL1 3859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.