Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22036321 | 0.96 | L3MBTL1 (0.46) | L3MBTL1ATMKDM4ETSPOKMT2A | |
| SCHEMBL22036139 | 0.95 | L3MBTL1 (0.43) | L3MBTL1ATMKDM4ETSPOKMT2A | |
| SCHEMBL23760169 | 0.95 | L3MBTL1 (0.47) | L3MBTL1ATMKDM4ETSPOKMT2A | |
| SCHEMBL23760161 | 0.95 | L3MBTL1 (0.47) | L3MBTL1ATMKDM4ETSPOKMT2A | |
| SCHEMBL22036719 | 0.91 | L3MBTL1 (0.44) | L3MBTL1ATMKDM4ETSPOKMT2A | |
| SCHEMBL22036718 | 0.89 | KDM4E (0.42) | L3MBTL1ATMKDM4EKMT2AIL1R1 | |
| SCHEMBL22035874 | 0.89 | L3MBTL1 (0.39) | L3MBTL1ATMKDM4EKMT2AIL1R1 | |
| SCHEMBL24797102 | 0.88 | KDM4E (0.35) | L3MBTL1ATMKDM4ETSPOKMT2A | |
| SCHEMBL24795005 | 0.86 | L3MBTL1 (0.53) | L3MBTL1ATMKDM4ETSPOKMT2A | |
| SCHEMBL22036701 | 0.86 | KDM4E (0.55) | L3MBTL1ATMKDM4EKMT2AIL1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630764-B1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR USE IN ELEKTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-08-18 | — | — | EP | disclosed |