Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | BUB1 | O43683 | 1/20 | 0.46 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | MARK3 | P27448 | 1/20 | 0.37 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.37 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18812369 | 0.91 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1PIK3R1PIK3CABCHE | |
| SCHEMBL26819799 | 0.90 | PIK3R1 (0.54) | HSP90AA1HSP90AB1PIK3R1PIK3CABCHE | |
| SCHEMBL24697208 | 0.90 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1PIK3R1PIK3CABCHE | |
| SCHEMBL14770848 | 0.88 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1PIK3R1PIK3CABCHE | |
| SCHEMBL28334293 | 0.88 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1PIK3R1PIK3CABCHE | |
| SCHEMBL28519533 | 0.87 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1PIK3R1PIK3CABCHE | |
| SCHEMBL17711777 | 0.87 | PIK3R1 (0.47) | HSP90AA1HSP90AB1PIK3R1PIK3CABCHE | |
| SCHEMBL13628889 | 0.87 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1PIK3R1PIK3CABCHE | |
| SCHEMBL28946565 | 0.86 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1PIK3R1PIK3CABCHE | |
| SCHEMBL15417099 | 0.86 | HSP90AA1 (0.53) | HSP90AA1HSP90AB1PIK3R1PIK3CABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535619-B2 | Hexacyclic heteroaromatic compounds for electronic devices | MERCK PATENT GMBH (DE) | 2022-12-27 | — | — | US | disclosed |
| US-20200165252-A1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165252-A1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR ELECTRONIC DEVICES | ETV6, CYP2J2, CYP2D6 | HSP90AA1 4224/4885HSP90AB1 4563/4885PIK3R1 3554/4885 |
| US-11535619-B2 | Hexacyclic heteroaromatic compounds for electronic devices | ETV6, CYP2J2, CYP2D6 | HSP90AA1 4224/4885HSP90AB1 4563/4885PIK3R1 3554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.