SCHEMBL14770848

SCHEMBL14770848

COc1ccccc1-c1cccn1C(=O)OC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 2/20 0.47
HSP90AB1 P08238 2/20 0.47
PIK3R1 P27986 1/20 0.45
PIK3CA P42336 1/20 0.45
MET P08581 1/20 0.43
AXL P30530 1/20 0.43
MERTK Q12866 1/20 0.43
BCHE P06276 2/20 0.40
BUB1 O43683 1/20 0.40
TNK2 Q07912 1/20 0.39
JAK1 P23458 1/20 0.39
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HDAC6 Q9UBN7 1/20 0.36
DRD2 P14416 1/20 0.36
RIPK2 O43353 1/20 0.36
ATR Q13535 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22036737 0.88 HSP90AA1 (0.53) HSP90AA1HSP90AB1PIK3R1PIK3CAMET
SCHEMBL3693171 0.88 HSP90AA1 (0.45) HSP90AA1HSP90AB1PIK3R1PIK3CAMET
SCHEMBL19953372 0.87 HSP90AA1 (0.51) HSP90AA1HSP90AB1PIK3R1PIK3CAMET
SCHEMBL14770871 0.84 HSP90AA1 (0.49) HSP90AA1HSP90AB1PIK3R1PIK3CAMET
SCHEMBL19718909 0.84 MET (0.47) HSP90AA1HSP90AB1PIK3R1PIK3CAMET
SCHEMBL18812369 0.83 HSP90AA1 (0.49) HSP90AA1HSP90AB1PIK3R1PIK3CAMET
SCHEMBL24697208 0.82 HSP90AA1 (0.48) HSP90AA1HSP90AB1PIK3R1PIK3CAMET
SCHEMBL26819799 0.82 PIK3R1 (0.54) HSP90AA1HSP90AB1PIK3R1PIK3CAMET
SCHEMBL5991785 0.81 HSP90AA1 (0.44) HSP90AA1HSP90AB1PIK3R1PIK3CAMET
SCHEMBL31518171 0.81 JAK2 (0.45) HSP90AA1HSP90AB1PIK3R1PIK3CAMET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013035303-A1 ORGANIC THIN FILM SOLAR CELL MATERIAL 出光興産株式会社 (JP) 2013-03-14 WO disclosed