Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14799190 | 0.82 | NPC1 (0.56) | MAPTSMN1; SMN2KMT2AL3MBTL1NPC1 | |
| SCHEMBL10919924 | 0.81 | CES2 (0.59) | CES2CES1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL3997033 | 0.81 | CES2 (0.52) | CES2CES1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL31757987 | 0.80 | ALDH1A1 (0.52) | MAPTSMN1; SMN2KMT2AL3MBTL1TSHR | |
| SCHEMBL497126 | 0.78 | — | — | |
| SCHEMBL28738208 | 0.78 | KMT2A (0.67) | CES2CES1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL1200128 | 0.78 | ERCC5 (0.54) | CES2CES1MAPTSMN1; SMN2KMT2A | |
| Methoxymethane SCHEMBL28663658 | 0.77 | KMT2A (0.45) | CES2CES1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL7647867 | 0.77 | CES2 (0.62) | CES2CES1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL3268211 | 0.77 | CES2 (0.62) | CES2CES1MAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104530014-A | 2-oxo-1,2-dihydrobenzo[cd] indole-6-sulfamide compound and composition and application thereof | GUANGZHOU INST BIOMED & HEALTH | 2015-04-22 | — | — | CN | claimed |
| CN-114728917-B | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-111971277-B | Benzothiophenes and related compounds as STING agonists | 默沙东有限责任公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-115677831-A | Peptidomimetic STAT degradation drug, composition and application | 杭州和正医药有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115087658-A | Sulfonamide or sulfenamide compounds having BRD 4-inducing proteolytic activity, and pharmaceutical use thereof | 田边三菱制药株式会社 | 2022-09-20 | — | — | CN | disclosed |
| CN-114728917-A | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-110036001-B | Benzo [ b ] thiophene compounds as STING agonists | 默沙东公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-106459055-B | Difunctional cytotoxic drug agent | PFIZER INC. (US) | 2019-11-01 | — | — | CN | disclosed |
| CN-106928252-B | A kind of compound and the preparation method and application thereof inhibiting ROCK | 成都先导药物开发股份有限公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-110115365-A | The adjusting that actinism receptor and relative ligand are carried out | 西诺米克斯公司 | 2019-08-13 | — | — | CN | disclosed |
| CN-1155558-C | N-alkoxyalkyl-N, N-dialkylamine derivatives or salts thereof, and therapeutic agents for neurodegenerative diseases containing the same | ��ɽ��ѧ��ҵ��ʽ���� | 2004-06-30 | — | — | CN | disclosed |
| CN-1489589-A | Novel carbapenem compounds | ס����ҩ��ʽ���� | 2004-04-14 | — | — | CN | disclosed |
| CN-1476429-A | EP4 receptor selective agonists in treatment of osteoporosis | �Ʒ� | 2004-02-18 | — | — | CN | disclosed |
| CN-1358169-A | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO LTD (JP) | 2002-07-10 | — | — | CN | disclosed |
| CN-1241176-A | Prevention of loss and restoration of bone mass by certain prostaglandin agonists | PFIZER (US) | 2000-01-12 | — | — | CN | disclosed |
| EP-0530579-B1 | Condensed pyrimidine derivatives antitumor agents | EISAI CO LTD (JP) | 1998-11-11 | — | — | EP | disclosed |
| US-5688800-A | ANTITUMOR AGENTS | EISAI CO., LTD. (JP) | 1997-11-18 | — | — | US | disclosed |
| US-5554615-A | ANTITUMOR | EISAI CO., LTD. (JP) | 1996-09-10 | — | — | US | disclosed |
| CN-1070402-A | The pyrimidine derivatives of condensation | EISAI CO LTD (JP) | 1993-03-31 | — | — | CN | disclosed |
| EP-0530579-A1 | Condensed pyrimidine derivatives antitumor agents | Eisai Co., Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |