SCHEMBL220369

SCHEMBL220369

CCCCCC(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 2/20 0.47
PPARG P37231 3/20 0.46
PTGES O14684 2/20 0.46
ALOX5 P09917 2/20 0.46
GAA P10253 6/20 0.44
KMT2A Q03164 3/20 0.44
GRIK1 P39086 2/20 0.42
GRIK2 Q13002 2/20 0.42
SLC1A2 P43004 1/20 0.42
SLC1A1 P43005 1/20 0.42
MAPK1 P28482 2/20 0.41
CA2 P00918 1/20 0.41
ALDH1A1 P00352 2/20 0.41
TSHR P16473 2/20 0.41
MEN1 O00255 2/20 0.41
ATM Q13315 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
USP2 O75604 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18662878 0.99 HMGCR (0.46) HMGCRPPARGPTGESALOX5GAA
SCHEMBL208069 0.99 HMGCR (0.46) HMGCRPPARGPTGESALOX5GAA
SCHEMBL8954906 0.99 HMGCR (0.46) HMGCRPPARGPTGESALOX5GAA
SCHEMBL5415838 0.99 HMGCR (0.46) HMGCRPPARGPTGESALOX5GAA
SCHEMBL21616894 0.99 HMGCR (0.46) HMGCRPPARGPTGESALOX5GAA
SCHEMBL11459320 0.99 HMGCR (0.46) HMGCRPPARGPTGESALOX5GAA
SCHEMBL17491249 0.99 HMGCR (0.46) HMGCRPPARGPTGESALOX5GAA
SCHEMBL284122 0.99 HMGCR (0.46) HMGCRPPARGPTGESALOX5GAA
SCHEMBL18855 0.99 HMGCR (0.46) HMGCRPPARGPTGESALOX5GAA
SCHEMBL17491360 0.99 HMGCR (0.46) HMGCRPPARGPTGESALOX5GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 922 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11932746-B2 Composition SI GROUP, INC. (US) 2024-03-19 US claimed
US-11879050-B2 Antidegradant blend SI GROUP, INC. (US) 2024-01-23 US claimed
US-20240010836-A1 POLYAMIDE PARTS WITH LOW FUEL PERMEATION EMS-CHEMIE AG (CH) 2024-01-11 US claimed
EP-4303259-A1 POLYAMIDE PARTS WITH LOW FUEL PERMEATION EMS-CHEMIE AG (CH) 2024-01-10 EP claimed
US-20230090780-A1 Non-Dust Blend SI GROUP, INC. 2023-03-23 US claimed
US-11572455-B2 Antidegradant blend SI GROUP, INC. (US) 2023-02-07 US claimed
EP-4097174-A1 NON-DUST BLEND SI Group Switzerland (CHAA) GmbH (CH) 2022-12-07 EP claimed
US-20220185986-A1 ANTIDEGRADANT BLEND SI GROUP, INC. 2022-06-16 US claimed
EP-3976701-A1 ANTIDEGRADANT BLEND SI Group Switzerland (CHAA) GmbH (CH) 2022-04-06 EP claimed
US-20210292649-A1 COMPOSITION SI GROUP, INC. 2021-09-23 US claimed
US-5780545-A A BLEND OF NON-POLY(ALKYLENE OXIDE)-FUNCTIONALIZED POLY(ORGANOSILOXANE) FLUID AND POLY(ALKYLENE OXIDE)-FUNCTIONALIZED POLY(ORGANOSILOXANE) FLUID AND AN ANTIOXIDANT; NON-SEPARATING, ODORLESS, ANTIFOULING FOR TONERS EASTMAN KODAK COMPANY (US) 1998-07-14 US claimed
US-5770115-A POLYPHENOLIC ANTIOXIDANT, UV ABSORBER, HINDERED AMINE LIGHT STABILIZER, NAPHTHOPYRAN DYE PPG INDUSTRIES, INC. (US) 1998-06-23 US claimed
EP-0613923-A1 Stabilized polyethylen moulding composition, process of preparation and its use HOECHST AKTIENGESELLSCHAFT (DE) 1994-09-07 EP claimed
EP-0173416-B1 HOT MELT BUTYLENE-ETHYLENE COPOLYMER ADHESIVES SHELL OIL COMPANY (US) 1991-11-06 EP claimed
EP-0173415-B1 HOT MELT BUTYLENE-ETHYLENE COPOLYMER ADHESIVES SHELL OIL COMPANY (US) 1989-12-20 EP claimed
EP-0173415-A2 Hot melt butylene-ethylene copolymer adhesives SHELL OIL COMPANY (US) 1986-03-05 EP claimed
EP-0173416-A2 Hot melt butylene-ethylene copolymer adhesives SHELL OIL COMPANY (US) 1986-03-05 EP claimed
US-4571410-A BELND OF TWO ETHYLENE-VINYL ACETATE COPOLYMERS CONTAING DIFFERENT CONCENTRATION OF VINYL ACETATE MAGIC SEAL CORPORATION (US) 1986-02-18 US claimed
US-4568713-A LONG OPEN TIME AND GOOD COLD METAL BONDING SHELL OIL COMPANY (US) 1986-02-04 US claimed
US-4554304-A LONG OPEN TIME SHELL OIL COMPANY (US) 1985-11-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210292649-A1 COMPOSITION GPX4, TXN2, TXNRD2 HMGCR 1101/4885PPARG 567/4885PTGES 599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.