Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | INPPL1 | O15357 | 4/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22037220 | 0.92 | SCN10A (0.39) | INPPL1SLC22A12XDHMKNK2AKT1 | |
| SCHEMBL22037628 | 0.91 | SLC22A12 (0.38) | SLC22A12MKNK2AKT1 | |
| SCHEMBL22037225 | 0.86 | MKNK1 (0.42) | MAPK1MKNK2MAPT | |
| SCHEMBL22037271 | 0.82 | SIRT2 (0.36) | — | |
| SCHEMBL22038671 | 0.80 | SLC22A12 (0.38) | SLC22A12VEGFAFLT1EGLN1EGLN3 | |
| SCHEMBL22038179 | 0.80 | FFAR1 (0.40) | SLC22A12AXLKDRIRAK4 | |
| SCHEMBL22038653 | 0.79 | PPARG (0.36) | SLC22A12MAPTRAB9A | |
| SCHEMBL22038774 | 0.79 | SLC22A12 (0.43) | SLC22A12CHEK2CSNK1DMAPTRAB9A | |
| SCHEMBL22038759 | 0.79 | FFAR1 (0.39) | SLC22A12MAPTGRIN2BRAB9A | |
| SCHEMBL22037673 | 0.78 | FFAR1 (0.38) | SLC22A12CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2990404-B1 | TETRAZOLINONE COMPOUND AND USE OF SAME | SUMITOMO CHEMICAL CO (JP) | 2020-05-27 | — | — | EP | disclosed |