Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22038682 | 0.87 | SIRT2 (0.37) | SIRT2SIRT3ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL22037628 | 0.86 | SLC22A12 (0.38) | SIRT2SIRT3SIRT1 | |
| SCHEMBL20195399 | 0.84 | FFAR1 (0.37) | ALDH1A1LMNACYP1A2 | |
| SCHEMBL22037225 | 0.83 | MKNK1 (0.42) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL22037220 | 0.83 | SCN10A (0.39) | — | |
| SCHEMBL22037640 | 0.82 | GRM5 (0.37) | — | |
| SCHEMBL22037199 | 0.80 | GABRA5 (0.33) | ALDH1A1LMNA | |
| SCHEMBL22038204 | 0.79 | PARP15 (0.39) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21317993 | 0.78 | PARP15 (0.41) | ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL22037708 | 0.78 | HTR7 (0.42) | LMNACYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2990404-B1 | TETRAZOLINONE COMPOUND AND USE OF SAME | SUMITOMO CHEMICAL CO (JP) | 2020-05-27 | — | — | EP | disclosed |