SCHEMBL22037673

SCHEMBL22037673

Cc1cccc(N(N)C(=O)N(C)N)c1COc1cccc(-c2ccsc2)c1

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.38
SLC22A12 Q96S37 1/20 0.37
CHEK2 O96017 3/20 0.36
SLC6A9 P48067 1/20 0.35
MC4R P32245 1/20 0.35
PTGER4 P35408 1/20 0.34
SQLE Q14534 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22038182 0.81 HTR7 (0.36) CHEK2
SCHEMBL22038759 0.81 FFAR1 (0.39) FFAR1SLC22A12
SCHEMBL22037244 0.80 HSD17B2 (0.39) FFAR1SLC22A12PTGER4
SCHEMBL22038179 0.80 FFAR1 (0.40) FFAR1SLC22A12
SCHEMBL22038774 0.80 SLC22A12 (0.43) FFAR1SLC22A12CHEK2
SCHEMBL22037628 0.79 SLC22A12 (0.38) FFAR1SLC22A12PTGER4
SCHEMBL22037640 0.78 GRM5 (0.37) SLC22A12CHEK2
SCHEMBL22038712 0.78 ICMT (0.43) FFAR1SLC22A12
SCHEMBL22038772 0.77 FFAR1 (0.39) FFAR1SLC22A12
SCHEMBL22038748 0.77 SLC22A12 (0.35) FFAR1SLC22A12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2990404-B1 TETRAZOLINONE COMPOUND AND USE OF SAME SUMITOMO CHEMICAL CO (JP) 2020-05-27 EP disclosed