Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.51 |
| ▸ | FNTB | P49356 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP4 | P49662 | 1/20 | 0.42 |
| ▸ | CASP5 | P51878 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21243060 | 0.91 | FNTA (0.61) | FNTAFNTBNFKB1KCNH2NFKB2 | |
| SCHEMBL17992570 | 0.91 | FNTA (0.61) | FNTAFNTBNFKB1KCNH2NFKB2 | |
| SCHEMBL2120270 | 0.91 | FNTA (0.61) | FNTAFNTBNFKB1KCNH2NFKB2 | |
| SCHEMBL8752386 | 0.91 | FNTA (0.61) | FNTAFNTBNFKB1KCNH2NFKB2 | |
| Acetic Acid SCHEMBL2582613 | 0.90 | FNTA (0.60) | FNTAFNTBNFKB1KCNH2NFKB2 | |
| SCHEMBL9069884 | 0.89 | NFKB1 (0.58) | FNTAFNTBNFKB1KCNH2NFKB2 | |
| SCHEMBL9073533 | 0.89 | FNTA (0.51) | FNTAFNTBNFKB1KCNH2NFKB2 | |
| SCHEMBL10944464 | 0.88 | NFKB1 (0.55) | FNTAFNTBNFKB1KCNH2NFKB2 | |
| SCHEMBL10394983 | 0.87 | FNTA (0.49) | FNTAFNTBNFKB1KCNH2NFKB2 | |
| SCHEMBL28944685 | 0.87 | NFKB1 (0.54) | FNTAFNTBNFKB1KCNH2NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3656385-A1 | NON-HORMONAL STEROID MODULATORS OF NF-KB FOR TREATMENT OF DISEASE | ReveraGen BioPharma, Inc. (US) | 2020-05-27 | — | — | EP | disclosed |