SCHEMBL21243060

SCHEMBL21243060

CC(=O)OCC(=O)C1=CCC2C3CCC4=CC(=O)C=CC4(C)C3=CCC12C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.61
FNTB P49356 1/20 0.61
LMNA P02545 4/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
NFKB1 P19838 2/20 0.49
KCNH2 Q12809 2/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
NR3C1 P04150 2/20 0.42
HIF1A Q16665 6/20 0.41
ALDH1A1 P00352 3/20 0.41
CYP3A4 P08684 3/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
CYP2C9 P11712 2/20 0.41
CASP1 P29466 1/20 0.41
CASP4 P49662 1/20 0.41
CASP5 P51878 1/20 0.41
RGS12 O14924 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17992570 1.00 FNTA (0.61) FNTAFNTBLMNASMN1; SMN2NFKB1
SCHEMBL2120270 1.00 FNTA (0.61) FNTAFNTBLMNASMN1; SMN2NFKB1
SCHEMBL8752386 1.00 FNTA (0.61) FNTAFNTBLMNASMN1; SMN2NFKB1
Acetic Acid SCHEMBL2582613 0.99 FNTA (0.60) FNTAFNTBLMNASMN1; SMN2NFKB1
SCHEMBL12156704 0.91 FNTA (0.59) FNTAFNTBLMNASMN1; SMN2NFKB1
SCHEMBL25784983 0.91 FNTA (0.51) FNTAFNTBLMNASMN1; SMN2NFKB1
SCHEMBL22038641 0.91 FNTA (0.51) FNTAFNTBLMNASMN1; SMN2NFKB1
SCHEMBL10394983 0.89 FNTA (0.49) FNTAFNTBLMNASMN1; SMN2NFKB1
SCHEMBL9069884 0.88 NFKB1 (0.58) FNTAFNTBLMNASMN1; SMN2NFKB1
SCHEMBL9073533 0.87 FNTA (0.51) FNTAFNTBLMNASMN1; SMN2NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106987542-B Application of Arthrobacter simplex mutant strain in 1, 2-position dehydrogenation 浙江神洲药业有限公司 2020-05-26 CN claimed
US-20230028248-A1 METHOD FOR PREPARING 16ALPHA-HYDROXYPREDNISOLONE ZHEJIANG SHENZHOU PHARMACEUTICAL COMPANY LIMITED (CN) 2023-01-26 US disclosed
EP-4116314-A1 METHOD FOR PREPARING 16ALPHA-HYDROXYPREDNISOLONE Zhejiang Shenzhou Pharmaceutical Company Limited (CN) 2023-01-11 EP disclosed
CN-113666985-A Preparation method of triamcinolone acetonide 山东谷雨春生物科技有限公司 2021-11-19 CN disclosed
EP-3656385-A1 NON-HORMONAL STEROID MODULATORS OF NF-KB FOR TREATMENT OF DISEASE ReveraGen BioPharma, Inc. (US) 2020-05-27 EP disclosed
EP-2805720-B1 Non-hormonal steroid modulators of NF-KB for treatment of disease REVERAGEN BIOPHARMA INC (US) 2019-08-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230028248-A1 METHOD FOR PREPARING 16ALPHA-HYDROXYPREDNISOLONE HSD17B2, HSD11B1, CYP17A1 FNTA 315/4885FNTB 1099/4885LMNA 2198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.