Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19404042 | 0.87 | MALT1 (0.42) | PTPN1HSD17B10SMN1; SMN2KDM4EHPGD | |
| SCHEMBL20266985 | 0.79 | PTPN1 (0.52) | PTPN1HSD17B10CYP1A2CYP2C9KDM4E | |
| SCHEMBL20267071 | 0.77 | PTPN1 (0.51) | PTPN1TSHRHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL19403986 | 0.77 | CYP3A4 (0.45) | PTPN1TSHRHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL22307347 | 0.77 | PTPN1 (0.54) | PTPN1HSD17B10CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL26198577 | 0.75 | GAA (0.58) | TSHRRECQLSMN1; SMN2MEN1GAA | |
| SCHEMBL7185412 | 0.73 | PTPN1 (0.50) | PTPN1HSD17B10CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL18493700 | 0.71 | PTPN1 (0.45) | PTPN1HSD17B10CYP1A2CYP2C9KDM4E | |
| SCHEMBL17267000 | 0.70 | PTPN1 (0.79) | PTPN1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL31265773 | 0.70 | PTPN1 (0.85) | PTPN1SMN1; SMN2PTPN11LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11571409-B2 | Substituted phenylpyrrolecarboxamides with therapeutic activity in HIV | NEW YORK BLOOD CENTER, INC. (US) | 2023-02-07 | — | — | US | disclosed |
| US-20210093608-A1 | SUBSTITUTED PHENYLPYRROLECARBOXAMIDES WITH THERAPEUTIC ACTIVITY IN HIV | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, | 2021-04-01 | — | — | US | disclosed |
| US-10869856-B2 | Substituted phenylpyrrolecarboxamides with therapeutic activity in HIV | NEW YORK BLOOD CENTER, INC. (US) | 2020-12-22 | — | — | US | disclosed |
| US-20200163935-A1 | SUBSTITUTED PHENYLPYRROLECARBOXAMIDES WITH THERAPEUTIC ACTIVITY IN HIV | NEW YORK BLOOD CENTER, INC. | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210093608-A1 | SUBSTITUTED PHENYLPYRROLECARBOXAMIDES WITH THERAPEUTIC ACTIVITY IN HIV | PAH, NPEPPS, DNPEP | PTPN1 3550/4885CNR2 757/4885TSHR 4426/4885 |
| US-10869856-B2 | Substituted phenylpyrrolecarboxamides with therapeutic activity in HIV | PAH, NPEPPS, DNPEP | PTPN1 3550/4885CNR2 757/4885TSHR 4426/4885 |
| US-20200163935-A1 | SUBSTITUTED PHENYLPYRROLECARBOXAMIDES WITH THERAPEUTIC ACTIVITY IN HIV | PAH, NPEPPS, DNPEP | PTPN1 3550/4885CNR2 757/4885TSHR 4426/4885 |
| US-11571409-B2 | Substituted phenylpyrrolecarboxamides with therapeutic activity in HIV | PAH, NPEPPS, DNPEP | PTPN1 3550/4885CNR2 757/4885TSHR 4426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.