SCHEMBL17267000

SCHEMBL17267000

O=C(Nc1ccc(NC(=O)c2ccc(-c3ccccc3)[nH]2)cc1)c1ccc(-c2ccccc2)[nH]1

nearest known ligand 0.79

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 5/20 0.79
▸ PTPN11 Q06124 1/20 0.66
▸ BCAT2 O15382 1/20 0.50
▸ DEGS1 O15121 1/20 0.50
▸ NPC1 O15118 3/20 0.47
▸ RAB9A P51151 3/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.47
▸ LMNA P02545 1/20 0.47
▸ WNT3A P56704 1/20 0.47
▸ SIRT1 Q96EB6 1/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ POLB P06746 1/20 0.47
▸ TRPV1 Q8NER1 1/20 0.46
▸ ALOX15 P16050 1/20 0.46
▸ CDK2 P24941 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31265773 0.97 PTPN1 (0.85) PTPN1PTPN11BCAT2DEGS1NPC1
SCHEMBL308253 0.77 KDM4E (0.69) PTPN1KDM4E
SCHEMBL27699479 0.77 KDM4E (0.53) PTPN1PTPN11NPC1RAB9ASMN1; SMN2
SCHEMBL22307347 0.77 PTPN1 (0.54) PTPN1PTPN11NPC1RAB9ASMN1; SMN2
SCHEMBL13536564 0.76 PTPN1 (0.53) PTPN1NPC1RAB9ASMN1; SMN2LMNA
Hydrochloric Acid SCHEMBL6335114 0.76 KDM4E (0.67) PTPN1NPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL20266985 0.76 PTPN1 (0.52) PTPN1PTPN11LMNAKDM4EPOLB
SCHEMBL20267071 0.74 PTPN1 (0.51) PTPN1PTPN11MEN1KMT2AKDM4E
SCHEMBL6335111 0.74 PTPN1 (0.50) PTPN1PTPN11NPC1RAB9ASMN1; SMN2
SCHEMBL27884299 0.74 NQO2 (0.51) PTPN1BCAT2RAB9ALMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020149206-A1 METHOD FOR PRODUCING ACRYLIC RESIN FILM コニカミノルタ株式会社 2020-07-23 — — WO disclosed
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 — — US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 — — US disclosed
WO-2017099041-A1 POLYIMIDE FILM, FLEXIBLE PRINTED BOARD, LED LIGHTING DEVICE ETC. コニカミノルタ株式会社 2017-06-15 — — WO disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 — — US disclosed
EP-2944676-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-11-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE HRH3, HELZ, NBAS PTPN1 4643/4885PTPN11 4245/4885BCAT2 3899/4885
US-10012777-B2 Resin composition NBAS, WDR5, HRH3 PTPN1 4601/4885PTPN11 4318/4885BCAT2 3835/4885
US-20180203175-A1 TRIAZOLE COMPOUND H1-10, TTI2, H1-2 PTPN1 1647/4885PTPN11 1121/4885BCAT2 1904/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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