SCHEMBL2204094

SCHEMBL2204094

CCCN(CCC)CCCCN(CCOC(C)=O)Cc1ccc(CNCc2ncc[nH]2)cc1

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 3/20 0.57
TSHR P16473 1/20 0.36
FPR2 P25090 1/20 0.33
TLR7 Q9NYK1 1/20 0.33
BCHE P06276 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15162123 0.86 CXCR4 (0.56) CXCR4
Ethyl Acetate SCHEMBL2204091 0.85 CXCR4 (0.66) CXCR4FPR2
SCHEMBL1638213 0.85 CXCR4 (0.58) CXCR4BCHE
SCHEMBL12426515 0.85 CXCR4 (0.59) CXCR4
SCHEMBL1638175 0.83 CXCR4 (0.59) CXCR4
SCHEMBL2206056 0.82 CXCR4 (0.54) CXCR4FPR2
SCHEMBL2201357 0.82 CXCR4 (0.44) CXCR4TSHRFPR2
SCHEMBL1205320 0.81 CXCR4 (0.54) CXCR4TSHRTLR7BCHE
SCHEMBL1205067 0.81 CXCR4 (0.51) CXCR4TSHRTLR7BCHE
SCHEMBL2201359 0.81 CXCR4 (0.47) CXCR4TSHRBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977512-B2 Amine derivative, and production method and use thereof KUREHA CORPORATION (JP) 2011-07-12 US disclosed
US-20080293951-A1 Amin Derivative, and Production Method and Use Thereof KUREHA CORPORATION 2008-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293951-A1 Amin Derivative, and Production Method and Use Thereof BCAT2, BCAT1, MRPL9 CXCR4 2546/4885TSHR 2682/4885FPR2 1363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.