SCHEMBL22041008

SCHEMBL22041008

CC(C)N1C(=O)c2cccc(F)c2C1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.43
DDB1 Q16531 1/20 0.40
CRBN Q96SW2 1/20 0.40
USP2 O75604 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
ADRA1D P25100 1/20 0.38
ADRA1A P35348 1/20 0.38
ADRA1B P35368 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALPL P05186 1/20 0.37
LMNA P02545 2/20 0.37
TRPA1 O75762 1/20 0.36
GRM1 Q13255 1/20 0.36
GRM4 Q14833 1/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
PGR P06401 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24303350 0.81 USP2 (0.42) MAPTUSP2PGRANPEPDPP4
SCHEMBL31259865 0.80 DPP4 (0.51) MAPTUSP2LMNAKMT2AMEN1
SCHEMBL12420865 0.80 DPP4 (0.47) DDB1CRBNUSP2CA1CA2
SCHEMBL5326245 0.80 DPP4 (0.51) MAPTUSP2LMNAKMT2AMEN1
SCHEMBL28646985 0.79 KMT2A (0.43) USP2TDP1LMNATRPA1GRM1
SCHEMBL28078067 0.79 USP2 (0.40) MAPTUSP2CA1CA2CA7
SCHEMBL24303335 0.79 USP2 (0.36) MAPTUSP2TDP1KDM4E
SCHEMBL1040431 0.79 DPP4 (0.49) USP2CA1CA2TDP1LMNA
SCHEMBL24671111 0.77 ANPEP (0.45) USP2TDP1LMNAKMT2AMEN1
SCHEMBL166122 0.76 TDP1 (0.57) MAPTUSP2TDP1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200172527-A1 BENZOXAZINONE DERIVATIVES USEFUL AS HERBICIDES REDAG CROP PROT LTD (GB) 2020-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200172527-A1 BENZOXAZINONE DERIVATIVES USEFUL AS HERBICIDES CBR3, CBR1, CYP4X1 MAPT 4014/4885DDB1 2201/4885CRBN 2720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.