SCHEMBL28078067

SCHEMBL28078067

CC(C)N1C(=O)c2cccc(Br)c2C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CYP1B1 Q16678 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
LMNA P02545 2/20 0.37
HTT P42858 3/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM4E B2RXH2 2/20 0.36
GAA P10253 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
ANPEP P15144 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31259865 0.80 DPP4 (0.51) USP2LMNAKMT2AALDH1A1MEN1
SCHEMBL12420865 0.80 DPP4 (0.47) USP2CA1CA2CA7CA9
SCHEMBL5326245 0.80 DPP4 (0.51) USP2LMNAKMT2AALDH1A1MEN1
SCHEMBL28932675 0.79 UTS2R (0.40) CA1CA2CA7CA9LMNA
SCHEMBL28646985 0.79 KMT2A (0.43) USP2TDP1LMNAKMT2AALDH1A1
SCHEMBL22041008 0.79 MAPT (0.43) USP2CA1CA2CA7CA9
SCHEMBL1040431 0.79 DPP4 (0.49) USP2CA1CA2TDP1LMNA
SCHEMBL24671111 0.77 ANPEP (0.45) USP2CYP1B1TDP1LMNAKMT2A
SCHEMBL166122 0.76 TDP1 (0.57) USP2TDP1LMNAHTTKMT2A
SCHEMBL29381145 0.76 TDP1 (0.57) USP2TDP1LMNAHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105778058-A Conjugated polymer and preparation method thereof 中国科学院长春应用化学研究所 2016-07-20 CN disclosed