Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.79 |
| ▸ | MGLL | Q99685 | 8/20 | 0.74 |
| ▸ | ABHD6 | Q9BV23 | 6/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30302068 | 0.88 | FAAH (1.00) | FAAHMGLLABHD6 | |
| SCHEMBL20566605 | 0.88 | FAAH (1.00) | FAAHMGLLABHD6 | |
| SCHEMBL20503623 | 0.85 | FAAH (0.73) | FAAHMGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL30419852 | 0.85 | MGLL (1.00) | FAAHMGLLABHD6CYP2D6 | |
| SCHEMBL20567166 | 0.85 | MGLL (1.00) | FAAHMGLLABHD6CYP2D6 | |
| SCHEMBL30302146 | 0.85 | FAAH (0.80) | FAAHMGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL20567214 | 0.85 | FAAH (0.80) | FAAHMGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL21271364 | 0.84 | FAAH (0.71) | FAAHMGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL24971297 | 0.83 | FAAH (0.77) | FAAHMGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL15093918 | 0.81 | MGLL (0.73) | FAAHMGLLABHD6CYP2D6PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020112905-A1 | METHODS OF TREATING DISEASE WITH MAGL INHIBITORS | LUNDBECK LA JOLLA RESEARCH CENTER, INC. (US) | 2020-06-04 | — | — | WO | disclosed |