SCHEMBL2204288

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3701591	0.89	KDR (0.38)	KDRFLT1ENPP3RETDDR1
	SCHEMBL3699255	0.89	KDR (0.49)	KDRFLT1ENPP3GAAKDM4E
	SCHEMBL15663972	0.88	KDR (0.43)	KDRFLT1ENPP3PDGFRBKIT
	SCHEMBL3711144	0.85	KDR (0.48)	KDRFLT1ENPP3PDGFRBKIT
	SCHEMBL3700725	0.85	ENPP3 (0.46)	KDRENPP3GAAKDM4EPDE5A
	SCHEMBL15663721	0.84	KDR (0.42)	KDRFLT1ENPP3PDGFRBKIT
	SCHEMBL3777004	0.84	TGFBR1 (0.41)	KDRFLT1RETDDR1GAA
	SCHEMBL3698986	0.81	GAA (0.40)	KDRENPP3GAAMAPTHPGD
	SCHEMBL3704302	0.81	KDR (0.43)	KDRFLT1ENPP3PDGFRBKIT
	SCHEMBL2206807	0.81	KDR (0.38)	KDRFLT1ENPP3PDGFRBKIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.