SCHEMBL22043540

SCHEMBL22043540

C/C=C/c1nc(C)no1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12652725 0.76 MEN1 (0.33)
SCHEMBL25181084 0.73 ALDH1A1 (0.40)
SCHEMBL21039897 0.73 ALDH1A1 (0.40)
SCHEMBL18920649 0.71
SCHEMBL18920651 0.71
SCHEMBL22347751 0.65 CYP19A1 (0.50)
SCHEMBL22347748 0.65 CYP19A1 (0.50)
SCHEMBL13186847 0.60 ACHE (0.31)
Ammonia Solution, Strong SCHEMBL9296211 0.60
SCHEMBL23840370 0.59 GAA (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020113028-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FERROPTOSIS AND TREATING EXCITOTOXIC DISORDERS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2020-06-04 WO disclosed