Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.50 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21990041 | 0.80 | STING1 (0.48) | SLC22A12STING1RORCACHEALDH1A1 | |
| SCHEMBL21905610 | 0.79 | STING1 (0.55) | STING1RORCMAPTSMN1; SMN2TP53 | |
| SCHEMBL22043972 | 0.79 | STING1 (0.73) | STING1RORCMAPTSMN1; SMN2TP53 | |
| SCHEMBL21990178 | 0.78 | RORC (0.50) | RORCGAA | |
| SCHEMBL21990156 | 0.78 | STING1 (0.61) | STING1RORCMAPTSMN1; SMN2POLB | |
| SCHEMBL21932345 | 0.78 | STING1 (0.56) | SLC22A12STING1RORCMAPTSMN1; SMN2 | |
| SCHEMBL24296024 | 0.73 | STING1 (0.49) | SLC22A12STING1RORCMAPTSMN1; SMN2 | |
| SCHEMBL21905625 | 0.72 | STING1 (0.46) | STING1RORCACHEMAPTKDM4E | |
| SCHEMBL21972427 | 0.72 | STING1 (0.52) | STING1RORCALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL21606290 | 0.72 | MAPT (0.51) | STING1RORCALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200172483-A1 | HETEROCYCLIC SMALL MOLECULE MODULATORS OF HUMAN STING | CURADEV PHARMA LIMITED (GB) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172483-A1 | HETEROCYCLIC SMALL MOLECULE MODULATORS OF HUMAN STING | STING1, IRF3, CGAS | SLC22A12 3798/4885STING1 1/4885RORC 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.