SCHEMBL22044

SCHEMBL22044

O=C(Cl)C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9834881 1.00
SCHEMBL836624 0.78
SCHEMBL25227005 0.78
SCHEMBL25241362 0.78
SCHEMBL27587735 0.76 ALDH1A1 (0.30)
SCHEMBL7500210 0.75
SCHEMBL2217731 0.75
SCHEMBL11335286 0.75
SCHEMBL17477671 0.75
SCHEMBL10477245 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 564 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119874506-A Process for the preparation and continuous preparation of fluoroacetylhalides 福建永晶科技股份有限公司 2025-04-25 CN claimed
CN-118724711-A Synthesis process of ethyl difluorobromoacetate with high-efficiency bromine utilization 五恒化学有限公司 2024-10-01 CN claimed
CN-117263774-B Treatment method of1, 1-difluoro chloroethane high-boiling-point substance 丰镇市汇杰环保科技发展有限公司 2024-07-19 CN claimed
CN-118084656-A Synthesis method of difluoroacetyl chloride 湖南斯派克科技股份有限公司 2024-05-28 CN claimed
CN-117384096-A Preparation method of difluoro pyrazole acid 山东国邦药业有限公司 2024-01-12 CN claimed
CN-117263774-A Treatment method of 1, 1-difluoro chloroethane high-boiling-point substance 丰镇市汇杰环保科技发展有限公司 2023-12-22 CN claimed
CN-116496156-B Synthesis method of difluoroacetyl chloride 山东国邦药业有限公司 2023-09-22 CN claimed
CN-116496156-A Synthesis method of difluoroacetyl chloride 山东国邦药业有限公司 2023-07-28 CN claimed
CN-116396022-A Preparation method and application of high-strength and high-toughness geopolymer material 苏州北美国际高级中学 2023-07-07 CN claimed
EP-3503167-B1 ATOMIC LAYER ETCHING USING ACID HALIDE KANTO DENKA KOGYO KK (JP) 2022-08-31 EP claimed
EP-1928820-A2 A PROCESS FOR PREPARING ESTER OXAZOLIDINE COMPOUNDS AND THEIR CONVERSION TO FLORFENICOL Schering-Plough Ltd. (CH) 2008-06-11 EP claimed
WO-2007030405-A2 A PROCESS FOR PREPARING ESTER OXAZOLIDINE COMPOUNDS AND THEIR CONVERSION TO FLORFENICOL SCHERING-PLOUGH LTD. (CH) 2007-03-15 WO claimed
WO-2007030386-A2 AN IMPROVED PROCESS FOR PREPARING OXAZOLIDINE PROTECTED AMINODIOL COMPOUNDS USEFUL AS INTERMEDIATES TO FLORFENICOL SCHERING-PLOUGH LTD. (CH) 2007-03-15 WO claimed
US-20070055080-A1 Process for preparing ester oxazolidine compounds and their conversion to Florfenicol SCHERING-PLOUGH ANIMAL HEALTH CORP. 2007-03-08 US claimed
US-20070055067-A1 Process for preparing oxazolidine protected aminodiol compounds useful as intermediates to Florfenicol SCHERING-PLOUGH ANIMAL HEALTH CORP. 2007-03-08 US claimed
US-5905169-A OXIDATION OF POLYFLUOROALKYLDIHALOMETHANES WITH OXYGEN E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-05-18 US claimed
EP-0694526-B1 Process for preparation of fluorinated beta-keto ester ROHM & HAAS (US) 1998-10-07 EP claimed
WO-1996029298-A1 PROCESS FOR PRODUCING POLYFLUOROACYL COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-09-26 WO claimed
US-5493025-A Process for preparation of fluorinated beta-keto ester ROHM AND HAAS COMPANY (US) 1996-02-20 US claimed
EP-0694526-A1 Process for preparation of fluorinated beta-keto ester ROHM AND HAAS COMPANY (US) 1996-01-31 EP claimed