SCHEMBL836624

SCHEMBL836624

O=C(Cl)C(F)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25227005 1.00
SCHEMBL25241362 1.00
SCHEMBL9834881 0.78
SCHEMBL22044 0.78
SCHEMBL10453275 0.77
SCHEMBL30248639 0.75
SCHEMBL301084 0.75
SCHEMBL25169780 0.75
SCHEMBL3750293 0.75
SCHEMBL10583452 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116947797-B Fluorescent probe for two-photon detection of carboxylesterase, preparation method and application 山东师范大学 2025-05-30 CN claimed
CN-116947797-A Fluorescent probe for two-photon detection of carboxylesterase, preparation method and application 山东师范大学 2023-10-27 CN claimed
EP-4747243-A1 LIGANDS AND COMPOSITIONS AND METHODS OF USE THEREOF Baylor College of Medicine (US) 2026-05-27 EP disclosed
US-12570620-B2 Covalent inhibitors of creatine kinase (CK) and uses thereof for treating and preventing cancer DANA-FARBER CANCER INSTITUTE, INC. (US) 2026-03-10 US disclosed
US-20250320227-A1 MACROCYCLIC OREXIN RECEPTOR AGONISTS AND USES THEREOF JAZZ PHARMACEUTICALS IRELAND LTD (IE) 2025-10-16 US disclosed
US-20250206722-A1 SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS THE SCRIPPS RESEARCH INSTITUTE 2025-06-26 US disclosed
EP-4377295-B1 HALOACETHYDRAZIDES USEFUL AS AEP INHIBITORS HOFFMANN LA ROCHE (CH) 2025-06-11 EP disclosed
CN-116947797-B Fluorescent probe for two-photon detection of carboxylesterase, preparation method and application 山东师范大学 2025-05-30 CN disclosed
CN-119977892-A Preparation method and application of benzimidazole skeleton-containing compound 中国科学院上海药物研究所 2025-05-13 CN disclosed
EP-4532497-A1 MACROCYCLIC OREXIN RECEPTOR AGONISTS AND USES THEREOF Jazz Pharmaceuticals Ireland Limited (IE) 2025-04-09 EP disclosed
CN-119630664-A Macrocyclic orexin receptor agonists and uses thereof 爵士制药爱尔兰有限公司 2025-03-14 CN disclosed
US-4582918-A Preparation of intermediates for (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols SCHERING CORPORATION (US) 1986-04-15 US disclosed
WO-1986001799-A1 PREPARATION OF (THREO)-1-ARYL-2-ACYLAMIDO-3-FLUORO-1-PROPANOLS SCHERING CORPORATION (US) 1986-03-27 WO disclosed
EP-0055215-B1 FLUOROPYRROLIDINONES, PROCESS FOR THEIR PREPARATION, HERBICIDES CONTAINING THEM AND THEIR USE CIBA-GEIGY AG (CH) 1985-01-30 EP disclosed
EP-0055215-A1 Fluoropyrrolidinones, process for their preparation, herbicides containing them and their use CIBA-GEIGY AG (CH) 1982-06-30 EP disclosed
US-4232016-A 3-Fluorobenzodiazepines MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1980-11-04 US disclosed
US-4182760-A TRANQUILIZERS, SEDATIVES AND MUSCLE RELAXANTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-01-08 US disclosed
US-4141895-A Hydroxyquinazolines and their use as intermediates for pharmaceutical agents E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-02-27 US disclosed
EP-0000332-A2 Benzophenone anti-oximes, diazepin-N-oxides, their preparations and their use as pharmaceutical agents and as intermediates for the preparation of diazepines E.I. DU PONT DE NEMOURS AND COMPANY (US) 1979-01-24 EP disclosed
US-4122115-A FROM THE ACETIC ACID AND CHLOROSULFONIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-10-24 US disclosed