Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22044000 | 0.90 | HPGD (0.47) | MMP13HTTALDH1A1HPGDLMNA | |
| SCHEMBL5537482 | 0.89 | ADORA2A (0.52) | ROCK2CDC7PRKACAGSK3BCLK4 | |
| SCHEMBL22044554 | 0.88 | MAPK1 (0.55) | ROCK2LMNAMAPK3MAPK1NPC1 | |
| SCHEMBL22044872 | 0.88 | NAMPT (0.44) | ROCK2HTTALDH1A1HPGDMAPK3 | |
| SCHEMBL22044085 | 0.88 | ROCK2 (0.47) | ROCK2CDC7CDK2HTTMAPK3 | |
| SCHEMBL22044073 | 0.88 | POLB (0.47) | HTTRXFP1ALDH1A1HPGDLMNA | |
| SCHEMBL22044478 | 0.88 | MMP13 (0.53) | MMP13ROCK2PRKACAGSK3BCLK4 | |
| SCHEMBL22044851 | 0.86 | MEN1 (0.52) | ROCK2CDC7PIM1PRKACACDK2 | |
| SCHEMBL22044474 | 0.86 | ROCK2 (0.49) | ROCK2MAPK3MAPK1 | |
| SCHEMBL22044004 | 0.85 | ADORA2A (0.43) | ROCK2HTTALDH1A1HPGDMAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210228552-A1 | METHOD FOR ADJUSTING RAS UBIQUITINATION | XIAMEN UNIVERSITY (CN) | 2021-07-29 | — | — | US | disclosed |
| EP-3786304-A1 | METHOD FOR ADJUSTING RAS UBIQUITINATION | Xiamen University (CN) | 2021-03-03 | — | — | EP | disclosed |
| US-20200172521-A1 | Five-Membered-Fused-Six-Membered Aza-Aromatic Ring Compound, Preparation Method Thereof, Pharmaceutical Composition And Application Thereof | Amcure Biosciences Pte. Ltd. (SG) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210228552-A1 | METHOD FOR ADJUSTING RAS UBIQUITINATION | NEDD4, KRAS, UBE3A | MMP13 4486/4885ROCK2 1663/4885CDC7 531/4885 |
| US-20200172521-A1 | Five-Membered-Fused-Six-Membered Aza-Aromatic Ring Compound, Preparation Method Thereof, Pharmaceutical Composition And Application Thereof | KRAS, NRAS, RASSF5 | MMP13 2778/4885ROCK2 1660/4885CDC7 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.