Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 10/20 | 0.52 |
| ▸ | MAPK3 | P27361 | 6/20 | 0.42 |
| ▸ | MAPK7 | Q13164 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22044457 | 0.94 | MAPK1 (0.47) | MAPK1MAPK3MAPK7MAPK14LMNA | |
| SCHEMBL22044081 | 0.90 | MAPK1 (0.53) | MAPK1MAPK3 | |
| SCHEMBL22043999 | 0.89 | ROCK2 (0.45) | MAPK1MAPK3MAPK7MAPK14ADORA2A | |
| SCHEMBL22044554 | 0.88 | MAPK1 (0.55) | MAPK1MAPK3MAPK7MAPK14NPC1 | |
| SCHEMBL22044458 | 0.88 | WDR5 (0.46) | MAPK1MAPK3NPC1LMNA | |
| SCHEMBL5536603 | 0.88 | TSHR (0.51) | MAPK1MAPK3NPC1ADORA2AITK | |
| SCHEMBL5537482 | 0.86 | ADORA2A (0.52) | MAPK1MAPK3MAPK7DYRK1BADORA2A | |
| SCHEMBL22044004 | 0.84 | ADORA2A (0.43) | MAPK1MAPK3MAPK7ADORA2AITK | |
| SCHEMBL22044077 | 0.84 | KDM4E (0.51) | MAPK1MAPK14NPC1LMNA | |
| SCHEMBL22044085 | 0.84 | ROCK2 (0.47) | MAPK1MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200172521-A1 | Five-Membered-Fused-Six-Membered Aza-Aromatic Ring Compound, Preparation Method Thereof, Pharmaceutical Composition And Application Thereof | Amcure Biosciences Pte. Ltd. (SG) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172521-A1 | Five-Membered-Fused-Six-Membered Aza-Aromatic Ring Compound, Preparation Method Thereof, Pharmaceutical Composition And Application Thereof | KRAS, NRAS, RASSF5 | MAPK1 3146/4885MAPK3 1726/4885MAPK7 1384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.