Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22050433 | 0.95 | CYP3A4 (0.45) | HSD17B10CYP3A4TAAR1TDP1MAPT | |
| SCHEMBL6836032 | 0.92 | TYR (0.42) | HSD17B10CYP3A4TAAR1TDP1MAPT | |
| SCHEMBL22043953 | 0.88 | CASP1 (0.41) | HSD17B10CYP3A4TDP1MAPTALDH1A1 | |
| SCHEMBL3184147 | 0.88 | CASP1 (0.43) | HSD17B10CYP3A4TDP1MAPTALDH1A1 | |
| SCHEMBL22051079 | 0.84 | TYR (0.44) | HSD17B10CYP3A4TDP1MAPTALDH1A1 | |
| SCHEMBL23054197 | 0.81 | TSHR (0.35) | HSD17B10CYP3A4TDP1MAPTALDH1A1 | |
| SCHEMBL22044609 | 0.79 | HSD17B10 (0.32) | HSD17B10CYP3A4TAAR1TDP1MAPT | |
| SCHEMBL22862181 | 0.78 | CYP3A4 (0.71) | HSD17B10CYP3A4TAAR1TDP1MAPT | |
| SCHEMBL19806864 | 0.78 | TYR (0.54) | CYP3A4TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL51614 | 0.78 | ALOX5 (0.55) | HSD17B10CYP3A4MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3659996-A1 | NOVEL (POLY)AMINE COMPOUND, RESIN, AND CURED PRODUCT | Mitsubishi Gas Chemical Company, Inc. (JP) | 2020-06-03 | — | — | EP | disclosed |