Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17666080 | 0.83 | NPC1 (0.42) | NPC1L3MBTL1PSMB5 | |
| SCHEMBL17666075 | 0.83 | NPC1 (0.42) | NPC1L3MBTL1PSMB5 | |
| SCHEMBL265222 | 0.80 | CA12 (0.39) | NPC1L3MBTL1 | |
| SCHEMBL20326163 | 0.76 | PSMB5 (0.33) | NPC1L3MBTL1PSMB5 | |
| SCHEMBL264900 | 0.74 | TDP1 (0.35) | NPC1L3MBTL1 | |
| SCHEMBL265272 | 0.73 | CA12 (0.43) | NPC1L3MBTL1 | |
| SCHEMBL104713 | 0.70 | NPC1 (0.48) | NPC1L3MBTL1PSMB5 | |
| SCHEMBL104712 | 0.70 | NPC1 (0.48) | NPC1L3MBTL1PSMB5 | |
| SCHEMBL14016335 | 0.69 | ALDH1A1 (0.30) | — | |
| SCHEMBL17666076 | 0.68 | NPC1 (0.41) | NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10669289-B2 | Boronic acid derivatives | MERCK PATENT GMBH (DE) | 2020-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10669289-B2 | Boronic acid derivatives | BCL9, BCL9L, BCL6 | NPC1 1247/4885L3MBTL1 356/4885PSMB5 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.