Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22046330 | 0.80 | ALDH1A1 (0.41) | MAPK1KDM4EALDH1A1NPC1KCNH2 | |
| SCHEMBL22046554 | 0.74 | ALDH1A1 (0.45) | MAPK1KDM4EALDH1A1NPC1MEN1 | |
| SCHEMBL22046556 | 0.71 | KCNH2 (0.50) | KDM4EALDH1A1KCNH2CYP2C8CYP2C9 | |
| SCHEMBL22045989 | 0.69 | ALDH1A1 (0.41) | MAPK1KDM4EALDH1A1NPC1MEN1 | |
| SCHEMBL4532023 | 0.63 | KDM4E (0.49) | MAPK1KDM4EALDH1A1NPC1LMNA | |
| SCHEMBL29936006 | 0.63 | KDM4E (0.49) | MAPK1KDM4EALDH1A1NPC1LMNA | |
| SCHEMBL21988981 | 0.62 | HCRTR2 (0.40) | MAPK1KDM4EALDH1A1NPC1KCNH2 | |
| SCHEMBL21988980 | 0.62 | HCRTR2 (0.40) | MAPK1KDM4EALDH1A1NPC1KCNH2 | |
| Formaldehyde SCHEMBL28745971 | 0.61 | KDM4E (0.46) | MAPK1KDM4EALDH1A1NPC1LMNA | |
| SCHEMBL21988921 | 0.61 | KDM4E (0.40) | MAPK1KDM4EALDH1A1NPC1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020109994-A1 | PYRAZOLES AS MODULATORS OF HEMOGLOBIN | PFIZER INC. (US) | 2020-06-04 | — | — | WO | disclosed |