Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.82 |
| ▸ | NPC1 | O15118 | 9/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.82 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.82 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.82 |
| ▸ | RELA | Q04206 | 5/20 | 0.82 |
| ▸ | MAPT | P10636 | 5/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.82 |
| ▸ | MEN1 | O00255 | 3/20 | 0.82 |
| ▸ | RECQL | P46063 | 1/20 | 0.82 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | TP53 | P04637 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32674578 | 1.00 | RAB9A (0.82) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL28433989 | 0.84 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL28617023 | 0.82 | RAB9A (0.77) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL27920671 | 0.82 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL28438775 | 0.81 | GRM5 (0.64) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL18963259 | 0.81 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL21446852 | 0.80 | ABCG2 (0.76) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL21446853 | 0.79 | RAB9A (0.77) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL17737453 | 0.79 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL6037573 | 0.79 | RAB9A (0.77) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156683-B | Synthesis method of quinoline oxide | 青岛农业大学 | 2020-06-26 | — | — | CN | disclosed |
| WO-2020109524-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-06-04 | — | — | WO | disclosed |