Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.77 |
| ▸ | NPC1 | O15118 | 11/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.77 |
| ▸ | TP53 | P04637 | 4/20 | 0.77 |
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | HPGD | P15428 | 2/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.65 |
| ▸ | RELA | Q04206 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.57 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18963259 | 0.87 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL21446852 | 0.86 | ABCG2 (0.76) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL21446853 | 0.86 | RAB9A (0.77) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL22046074 | 0.82 | RAB9A (0.82) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL32674578 | 0.82 | RAB9A (0.82) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL12090707 | 0.81 | GRM5 (0.59) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL29643946 | 0.81 | GRM5 (0.59) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL27920671 | 0.79 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL1131467 | 0.79 | SMN1; SMN2 (1.00) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL29643927 | 0.78 | POLB (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459438-A | Synthesis method of iodine-catalyzed N-acyl-2-hydroxy-indol-3-one compound | 延安大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-113278007-B | Synthetic method of 2-hydroxy-indole-3-ketone compound | 延安大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-113278007-A | Synthetic method of 2-hydroxy-indole-3-ketone compound | 延安大学 | 2021-08-20 | — | — | CN | disclosed |