Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | UBE2N | P61088 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11640562 | 0.76 | OPRM1 (0.37) | OPRM1SPHK1TP53 | |
| SCHEMBL12133360 | 0.68 | GAA (0.33) | OPRM1SPHK1TP53CYP2D6GMNN | |
| SCHEMBL12134650 | 0.67 | CYP2D6 (0.34) | SPHK1TP53CYP2D6GMNNLMNA | |
| SCHEMBL17037031 | 0.66 | — | — | |
| SCHEMBL23603529 | 0.65 | OPRM1 (0.52) | OPRM1SPHK1TP53CYP2D6GMNN | |
| Hexane SCHEMBL10952643 | 0.65 | OPRM1 (0.65) | OPRM1SPHK1TP53LMNA | |
| SCHEMBL530709 | 0.62 | — | — | |
| SCHEMBL9189870 | 0.62 | GRIN2D (0.32) | — | |
| Heptane SCHEMBL17633521 | 0.62 | TSHR (0.61) | OPRM1SPHK1TP53 | |
| Dodecane SCHEMBL28202232 | 0.62 | TSHR (0.61) | OPRM1SPHK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3359564-B1 | ANTIBODIES THAT POTENTLY NEUTRALIZE HEPATITIS B VIRUS AND USES THEREOF | HUMABS BIOMED S A (CH) | 2020-06-03 | — | — | EP | disclosed |