Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17037031 | 0.85 | — | — | |
| SCHEMBL9189870 | 0.81 | GRIN2D (0.32) | — | |
| SCHEMBL22046096 | 0.76 | OPRM1 (0.38) | OPRM1SPHK1TP53 | |
| SCHEMBL28131390 | 0.73 | SLC6A4 (0.33) | OPRM1 | |
| SCHEMBL9189986 | 0.71 | SLC6A4 (0.31) | — | |
| SCHEMBL12133358 | 0.70 | GAA (0.32) | OPRM1 | |
| SCHEMBL14670241 | 0.70 | OPRM1 (0.30) | OPRM1 | |
| SCHEMBL28095873 | 0.70 | CETP (0.33) | — | |
| SCHEMBL1551618 | 0.69 | SHBG (0.32) | — | |
| SCHEMBL12134653 | 0.68 | CYP2D6 (0.31) | SPHK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4102890-A | HYPNOTIC, ANALGESIC, HYPOTENSIVE, CARDIOVASCULAR DEPRESSANTS, NEURO-MODULATORS | SCIENCE-UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1978-07-25 | — | — | US | disclosed |