Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22579415 | 0.90 | HRH3 (0.41) | CRBNHRH3HCRTR2ALDH1A1MEN1 | |
| SCHEMBL31704833 | 0.83 | LRRK2 (0.40) | CRBNHRH3HCRTR2ALDH1A1FFAR2 | |
| SCHEMBL14164278 | 0.83 | HRH3 (0.38) | CRBNHRH3HCRTR2ALDH1A1MEN1 | |
| SCHEMBL31706232 | 0.83 | PLAT (0.41) | CRBNHRH3HCRTR2MEN1KMT2A | |
| SCHEMBL14164237 | 0.83 | PLAT (0.41) | CRBNHRH3HCRTR2MEN1KMT2A | |
| SCHEMBL14164274 | 0.82 | HRH3 (0.37) | CRBNHRH3HCRTR2ALDH1A1MEN1 | |
| SCHEMBL14164234 | 0.82 | HRH3 (0.42) | CRBNHRH3HCRTR2SMN1; SMN2HTT | |
| SCHEMBL628287 | 0.81 | GSK3B (0.37) | HRH3HCRTR2 | |
| SCHEMBL745563 | 0.75 | GRM5 (0.43) | CRBNALDH1A1HTTHPGDL3MBTL1 | |
| SCHEMBL14164236 | 0.75 | GPR119 (0.48) | CRBNHRH3ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020108579-A1 | AMINO-SUBSTITUTED PYRIDONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 上海海雁医药科技有限公司 | 2020-06-04 | — | — | WO | disclosed |