Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | MAP4K3 | Q8IVH8 | 3/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14164237 | 1.00 | PLAT (0.41) | PLATHTR2CCRBNHRH3MAP4K3 | |
| SCHEMBL22579415 | 0.90 | HRH3 (0.41) | CRBNHRH3MEN1KMT2AHCRTR2 | |
| SCHEMBL31705326 | 0.85 | HCRTR2 (0.48) | PLATMAP4K3HCRTR2 | |
| SCHEMBL15376175 | 0.85 | HCRTR2 (0.48) | PLATMAP4K3HCRTR2 | |
| SCHEMBL31704833 | 0.83 | LRRK2 (0.40) | CRBNHRH3HCRTR2FFAR2 | |
| SCHEMBL14164278 | 0.83 | HRH3 (0.38) | CRBNHRH3MEN1KMT2AHCRTR2 | |
| SCHEMBL22048060 | 0.83 | CRBN (0.41) | CRBNHRH3MEN1KMT2AHCRTR2 | |
| SCHEMBL14164274 | 0.82 | HRH3 (0.37) | CRBNHRH3MEN1KMT2AHCRTR2 | |
| SCHEMBL14164234 | 0.82 | HRH3 (0.42) | CRBNHRH3CHEK1CHEK2HCRTR2 | |
| SCHEMBL3658788 | 0.80 | SLC6A2 (0.42) | MEN1KMT2AHCRTR2CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |