Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864229 | 0.81 | SRD5A1 (0.45) | SLC18A3AKR1C3AKR1C1SRD5A1MEN1 | |
| SCHEMBL22047874 | 0.79 | PDE4A (0.48) | — | |
| SCHEMBL3988360 | 0.77 | AKR1C3 (0.47) | SLC18A3AKR1C3AKR1C1SRD5A1MEN1 | |
| SCHEMBL22048252 | 0.74 | KDM4E (0.37) | KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL8920951 | 0.74 | SRD5A1 (0.46) | SLC18A3AKR1C3AKR1C1SRD5A1 | |
| SCHEMBL29730977 | 0.73 | — | — | |
| SCHEMBL16543144 | 0.73 | SLC18A3 (0.50) | SLC18A3AKR1C3AKR1C1 | |
| SCHEMBL18585014 | 0.73 | SRD5A1 (0.49) | SLC18A3AKR1C3AKR1C1SRD5A1SMN1; SMN2 | |
| SCHEMBL13039616 | 0.72 | SRD5A1 (0.47) | SLC18A3AKR1C3AKR1C1SRD5A1 | |
| SCHEMBL8384792 | 0.71 | SLC18A3 (0.55) | SLC18A3AKR1C3AKR1C1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020108579-A1 | AMINO-SUBSTITUTED PYRIDONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 上海海雁医药科技有限公司 | 2020-06-04 | — | — | WO | disclosed |