Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 4/20 | 0.32 |
| ▸ | METAP1 | P53582 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980155 | 0.83 | STAT3 (0.32) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL19980141 | 0.83 | STAT3 (0.32) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL20344524 | 0.80 | KIF11 (0.40) | ALDH1A1SLC6A4MEN1KMT2ALMNA | |
| SCHEMBL19980121 | 0.79 | SLC6A2 (0.40) | KDM4EALDH1A1GAASLC6A4SLC6A2 | |
| SCHEMBL19980350 | 0.79 | SLC6A2 (0.40) | KDM4EALDH1A1GAASLC6A4SLC6A2 | |
| SCHEMBL21157263 | 0.77 | KDM4E (0.42) | KDM4EALDH1A1GLAGAASLC6A4 | |
| SCHEMBL20344529 | 0.77 | KMT2A (0.41) | ALDH1A1GAASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL19980150 | 0.75 | — | — | |
| SCHEMBL21156890 | 0.74 | KMT2A (0.38) | GAASLC6A4SLC6A2SLC6A3METAP2 | |
| SCHEMBL25900006 | 0.73 | KDM4E (0.45) | KDM4EALDH1A1GLAGAASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3375780-B1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2020-06-03 | — | — | EP | disclosed |