SCHEMBL22048844

SCHEMBL22048844

c1ccc2c(c1)c1ccccc1c1c3cnccc3c3ccccc3c21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 3/20 0.52
KDM4E B2RXH2 5/20 0.50
MAOA P21397 5/20 0.50
MAOB P27338 5/20 0.50
ALDH1A1 P00352 3/20 0.50
HPGD P15428 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
POLB P06746 2/20 0.50
HTT P42858 2/20 0.50
ACHE P22303 2/20 0.50
GABRP O00591 1/20 0.50
GABRD O14764 1/20 0.50
IKBKB O14920 1/20 0.50
AURKA O14965 1/20 0.50
CHUK O15111 1/20 0.50
PIM1 P11309 1/20 0.50
TOP1 P11387 1/20 0.50
GABRA1 P14867 1/20 0.50
IDO1 P14902 1/20 0.50
GABRB1 P18505 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17298998 0.89 PARP1 (0.55) PARP1KDM4EMAOAMAOBALDH1A1
SCHEMBL15374747 0.89 PARP1 (0.55) PARP1KDM4EMAOAMAOBALDH1A1
SCHEMBL743939 0.89 PARP1 (0.55) PARP1KDM4EMAOAMAOBALDH1A1
SCHEMBL15374721 0.89 PARP1 (0.55) PARP1KDM4EMAOAMAOBALDH1A1
SCHEMBL21297781 0.80 KDM4E (0.54) PARP1KDM4EMAOAMAOBALDH1A1
SCHEMBL21297780 0.80 KDM4E (0.59) PARP1KDM4EMAOAMAOBALDH1A1
SCHEMBL16231036 0.77 PARP1 (0.46) PARP1KDM4EMAOAMAOBALDH1A1
SCHEMBL16230973 0.77 PARP1 (0.46) PARP1KDM4EMAOAMAOBALDH1A1
SCHEMBL16231012 0.77 PARP1 (0.46) PARP1KDM4EMAOAMAOBALDH1A1
SCHEMBL262425 0.76 ALDH1A1 (0.59) KDM4EMAOAALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020111140-A1 FUSED RING COMPOUND, PRODUCTION METHOD THEREFOR, AND ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL 東ソー株式会社 2020-06-04 WO disclosed