SCHEMBL743939

SCHEMBL743939

c1ccc2c(c1)c1ccccc1c1cnccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 3/20 0.55
KDM4E B2RXH2 5/20 0.54
MAOA P21397 5/20 0.54
MAOB P27338 5/20 0.54
ACHE P22303 2/20 0.54
ALDH1A1 P00352 2/20 0.54
HPGD P15428 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
GABRP O00591 1/20 0.54
GABRD O14764 1/20 0.54
IKBKB O14920 1/20 0.54
AURKA O14965 1/20 0.54
CHUK O15111 1/20 0.54
PIM1 P11309 1/20 0.54
TOP1 P11387 1/20 0.54
GABRA1 P14867 1/20 0.54
IDO1 P14902 1/20 0.54
GABRB1 P18505 1/20 0.54
GABRG2 P18507 1/20 0.54
GABRB3 P28472 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17298998 1.00 PARP1 (0.55) PARP1KDM4EMAOAMAOBACHE
SCHEMBL15374721 1.00 PARP1 (0.55) PARP1KDM4EMAOAMAOBACHE
SCHEMBL15374747 1.00 PARP1 (0.55) PARP1KDM4EMAOAMAOBACHE
SCHEMBL21297781 0.90 KDM4E (0.54) PARP1KDM4EMAOAMAOBACHE
SCHEMBL22048844 0.89 PARP1 (0.52) PARP1KDM4EMAOAMAOBACHE
SCHEMBL16231036 0.86 PARP1 (0.46) PARP1KDM4EMAOAMAOBACHE
SCHEMBL16230973 0.86 PARP1 (0.46) PARP1KDM4EMAOAMAOBACHE
SCHEMBL16231012 0.86 PARP1 (0.46) PARP1KDM4EMAOAMAOBACHE
SCHEMBL21297780 0.85 KDM4E (0.59) PARP1KDM4EMAOAMAOBACHE
SCHEMBL20698679 0.84 NPC1 (0.48) PARP1KDM4EMAOAMAOBACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3356369-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING TRIAZINE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2022-05-04 EP claimed
US-20180269407-A1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING TRIAZINE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2018-09-20 US claimed
EP-3356369-A1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING TRIAZINE GROUPS FOR ORGANIC LIGHT EMITTING DIODES Idemitsu Kosan Co., Ltd (JP) 2018-08-08 EP claimed
WO-2007103884-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF MULTIPLE SCLEROSIS AMPLIMED CORPORATION (US) 2007-09-13 WO claimed
US-20070213354-A1 Compositions and Methods for the Treatment of Multiple Sclerosis AMPLIMED CORPORATION (US) 2007-09-13 US claimed
EP-1787985-A1 Azonafide derivatives, methods for their production and pharmaceutical compositions therefrom Unibioscreen S.A. (BE) 2007-05-23 EP claimed
US-7101530-B2 catalytically saturating polycyclic aromatic hydrocarbons for storage, then dehydrogenation with catalyst to release hydrogen; supplying hydrogen to fuel cells AIR PRODUCTS AND CHEMICALS, INC. (US) 2006-09-05 US claimed
EP-3715352-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2025-07-30 EP disclosed
US-20240341169-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-10-10 US disclosed
US-12022727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-06-25 US disclosed
US-20230365857-A1 ORGANIC MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-16 US disclosed
US-20230365857-A1 ORGANIC MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-16 US disclosed
US-20230131934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
WO-1994006771-A9 1,2 DIHYDRO-3-H-DIBENZ(de,h) ISOQUINOLINE 1,3 DIONE AND THEIR USE AS ANTICANCER AGENTS 1994-06-09 WO disclosed
WO-1994006771-A1 1,2 DIHYDRO-3-H-DIBENZ(de,h) ISOQUINOLINE 1,3 DIONE AND THEIR USE AS ANTICANCER AGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1994-03-31 WO disclosed
EP-0536208-A4 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS 1993-05-05 EP disclosed
EP-0536208-A1 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1993-04-14 EP disclosed
WO-1992000281-A1 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1992-01-09 WO disclosed
EP-0288399-A3 POLYESTERS HAVING IMPROVED WHITENESS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-03-07 EP disclosed
EP-0288399-A2 Polyesters having improved whiteness EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-10-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365857-A1 ORGANIC MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES H1-0, OR10J3, H1-2 PARP1 3776/4885KDM4E 3438/4885MAOA 79/4885
US-20240341169-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OSBP, OCIAD2 PARP1 1555/4885KDM4E 4507/4885MAOA 607/4885
US-20180269407-A1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING TRIAZINE GROUPS FOR ORGANIC LIGHT EMITTING DIODES ALDH1A2, TRPA1, CDK2 PARP1 3151/4885KDM4E 977/4885MAOA 845/4885
US-12022727-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 PARP1 1555/4885KDM4E 4507/4885MAOA 607/4885
US-20070213354-A1 Compositions and Methods for the Treatment of Multiple Sclerosis C9, CBR3, CHRM2 PARP1 3510/4885KDM4E 2622/4885MAOA 1995/4885
US-20230131934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP PARP1 1094/4885KDM4E 4278/4885MAOA 1466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.