Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22050576 | 0.79 | RAB9A (0.52) | MAPK1MAPTNPSR1HDAC2HDAC1 | |
| SCHEMBL4819210 | 0.73 | MAPK1 (0.55) | MAPK1MAPTNPSR1HDAC2HDAC1 | |
| SCHEMBL4819221 | 0.73 | MAPK1 (0.55) | MAPK1MAPTNPSR1HDAC2HDAC1 | |
| SCHEMBL16043901 | 0.67 | USP2 (0.47) | NAMPTMAPK1USP2EPHX2SMN1; SMN2 | |
| SCHEMBL3704083 | 0.65 | NAMPT (1.00) | NAMPT | |
| SCHEMBL9030697 | 0.64 | MEN1 (0.69) | MAPTNPSR1RAB9AMEN1KMT2A | |
| SCHEMBL23144507 | 0.64 | NAMPT (0.32) | NAMPTKMT2AALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9030247 | 0.64 | MEN1 (0.67) | MAPTNPSR1RAB9AMEN1KMT2A | |
| SCHEMBL4819216 | 0.63 | MAPT (0.46) | MAPK1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL29565909 | 0.63 | SMN1; SMN2 (0.50) | MAPK1USP2EPHX2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200171132-A1 | METHODS OF INHIBITING FUNGAL CERAMIDE SYNTHASE FOR TREATMENT OF CRYPTOCOCCUS NEOFORMANS INFECTION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200171132-A1 | METHODS OF INHIBITING FUNGAL CERAMIDE SYNTHASE FOR TREATMENT OF CRYPTOCOCCUS NEOFORMANS INFECTION | CERS2, CERT1, SMPD1 | NAMPT 140/4885MAPK1 1019/4885MAPT 3642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.