Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.49 |
| ▸ | S100A10 | P60903 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9030247 | 0.99 | MEN1 (0.67) | MEN1KMT2AALDH1A1TSHRPOLB | |
| SCHEMBL10677897 | 0.84 | MEN1 (0.56) | MEN1KMT2AALDH1A1TSHRPOLB | |
| SCHEMBL9808208 | 0.81 | MEN1 (0.55) | MEN1KMT2AALDH1A1TSHRPOLB | |
| SCHEMBL5751507 | 0.78 | ALDH1A1 (0.75) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL1442840 | 0.77 | POLB (0.55) | ALDH1A1TSHRPOLBPKMRAB9A | |
| SCHEMBL1080002 | 0.76 | MEN1 (0.65) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL20812868 | 0.76 | LMNA (0.57) | MEN1KMT2AALDH1A1TSHRPOLB | |
| SCHEMBL12964242 | 0.75 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL1441662 | 0.75 | ALDH1A1 (0.54) | KMT2AALDH1A1TSHRPOLBPKM | |
| SCHEMBL7279410 | 0.74 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727421-A1 | Agents for improving sleep | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-08-21 | — | — | EP | disclosed |
| EP-0285219-A2 | Method of improving sleep | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-10-05 | — | — | EP | disclosed |