Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 7/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.33 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22051934 | 0.93 | S1PR5 (0.39) | KMT2AS1PR5P2RY14KDM1AMAOA | |
| SCHEMBL22051332 | 0.91 | DRD2 (0.34) | P2RY14GRIN2BUSP5DRD2CCR2 | |
| SCHEMBL22050821 | 0.88 | MGLL (0.35) | KMT2AS1PR5P2RY14DRD2HTR1A | |
| SCHEMBL22051952 | 0.88 | USP5 (0.33) | P2RY14USP5DRD2 | |
| SCHEMBL23888898 | 0.87 | DRD2 (0.32) | P2RY14USP5DRD2CCR2 | |
| SCHEMBL23888887 | 0.85 | P2RY14 (0.38) | S1PR5P2RY14DRD2HTR1AADRA2A | |
| SCHEMBL22051258 | 0.84 | USP5 (0.46) | KMT2AUSP5 | |
| SCHEMBL22051935 | 0.77 | USP5 (0.51) | KMT2AS1PR5USP5 | |
| SCHEMBL22050486 | 0.77 | USP5 (0.51) | KMT2AS1PR5USP5 | |
| SCHEMBL23888878 | 0.77 | S1PR5 (0.40) | KMT2AS1PR5P2RY14KDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888651-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | Kyushu University, National University Corporation (JP) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020111252-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | 国立大学法人九州大学 | 2020-06-04 | — | — | WO | disclosed |