Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18699228 | 0.83 | CYP3A4 (0.39) | CYP3A4LMNA | |
| SCHEMBL17030400 | 0.72 | CHRM1 (0.36) | — | |
| Crotetamide SCHEMBL26015 | 0.71 | CYP3A4 (0.33) | CYP3A4LMNA | |
| Crotetamide SCHEMBL26013 | 0.71 | CYP3A4 (0.33) | CYP3A4LMNA | |
| SCHEMBL1535835 | 0.70 | — | — | |
| SCHEMBL11469132 | 0.69 | CYP3A4 (0.35) | CYP3A4LMNA | |
| SCHEMBL11445630 | 0.69 | CYP3A4 (0.35) | CYP3A4LMNA | |
| SCHEMBL22319040 | 0.69 | CYP3A4 (0.43) | CYP3A4LMNA | |
| SCHEMBL104712 | 0.69 | NPC1 (0.48) | CYP3A4LMNA | |
| SCHEMBL104713 | 0.69 | NPC1 (0.48) | CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020112937-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2020-06-04 | — | — | WO | disclosed |