Crotetamide

Crotetamide

SCHEMBL26015

CC=CC(=O)N(CC)C(CC)C(=O)N(C)C

nearest known ligand 0.33

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Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 2/20 0.33
▸ LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Crotetamide SCHEMBL26013 1.00 CYP3A4 (0.33) CYP3A4LMNA
Cropropamide SCHEMBL2967555 0.92 CYP3A4 (0.30) CYP3A4LMNA
Cropropamide SCHEMBL25324 0.87 — —
SCHEMBL18699228 0.74 CYP3A4 (0.39) CYP3A4LMNA
SCHEMBL22053010 0.71 CYP3A4 (0.40) CYP3A4LMNA
SCHEMBL25337345 0.69 FDPS (0.34) —
SCHEMBL9500561 0.68 TSHR (0.32) —
SCHEMBL16071866 0.66 — —
SCHEMBL28719684 0.66 — —
SCHEMBL12121535 0.66 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1017 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120063996-A1 NOVEL NIMESULIDE COMPOSITIONS ELAN PHARMA INTERNATIONAL LTD. 2012-03-15 — — US claimed
EP-1617816-B1 NANOPARTICULATE MELOXICAN FORMULATIONS ELAN PHARMA INT LTD (IE) 2009-05-13 — — EP claimed
EP-1981502-A2 PHARMACEUTICAL COMPOSITION CONTAINING A CENTRAL OPIOID AGONIST, A CENTRAL OPIOID ANTAGONIST, AND A PERIPHERAL OPIOID ANTAGONIST, AND METHOD FOR MAKING THE SAME Harrogate Holdings (BM) 2008-10-22 — — EP claimed
EP-1938803-A2 Formulations comprising nanoparticulate meloxican Elan Pharma International Limited (IE) 2008-07-02 — — EP claimed
CN-100346832-C Pharmaceutical dosage form for transmucosal delivery PHARMACIA CORP (US) 2007-11-07 — — CN claimed
WO-2007088489-A2 PHARMACEUTICAL COMPOSITION CONTAINING A CENTRAL OPIOID AGONIST, A CENTRAL OPIOID ANTAGONIST, AND A PERIPHERAL OPIOID ANTAGONIST, AND METHOD FOR MAKING THE SAME HARROGATE HOLDINGS (US) 2007-08-09 — — WO claimed
US-20070185145-A1 Pharmaceutical composition containing a central opioid agonist, a central opioid antagonist, and a peripheral opioid antagonist, and method for making the same HARROGATE HOLDINGS (BM) 2007-08-09 — — US claimed
EP-1480624-B1 PHARMACEUTICAL TABLET PHARMACIA CORP (US) 2006-11-29 — — EP claimed
EP-1471890-B1 PHARMACEUTICAL DOSAGE FORM FOR MUCOSAL DELIVERY PHARMACIA CORP (US) 2006-09-27 — — EP claimed
EP-1608407-B1 DISPERSIBLE FORMULATION OF AN ANTI-INFLAMMATORY AGENT PHARMACIA CORP (US) 2006-08-30 — — EP claimed
WO-2004082719-A1 DISPERSIBLE PHARMACEUTICAL COMPOSITION FOR TREATMENT OF MASTITIS AND OTIC DISORDERS PHARMACIA CORPORATION (US) 2004-09-30 — — WO claimed
US-20040156872-A1 Novel nimesulide compositions ELAN PHARMA INTERNATIONAL LTD. 2004-08-12 — — US claimed
US-20030235617-A1 Pharmaceutical dosage form for mucosal delivery MCNEIL-PPC, INC 2003-12-25 — — US claimed
US-20030180357-A1 Pharmaceutical tablet MCNEIL-PPC, INC 2003-09-25 — — US claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 — — EP claimed
WO-2003066029-A2 PHARMACEUTICAL DOSAGE FORM FOR MUCOSAL DELIVERY PHARMACIA CORPORATION (US) 2003-08-14 — — WO claimed
WO-2003066030-A2 PHARMACEUTICAL TABLET PHARMACIA CORPORATION (US) 2003-08-14 — — WO claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 — — CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 — — EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040156872-A1 Novel nimesulide compositions NIM1K, NIT2, NCL CYP3A4 1976/4885LMNA 3668/4885
US-20030180357-A1 Pharmaceutical tablet GYPA, SORD, SRI CYP3A4 306/4885LMNA 2379/4885
US-20120063996-A1 NOVEL NIMESULIDE COMPOSITIONS NIM1K, NIT2, NCL CYP3A4 1976/4885LMNA 3668/4885
US-20030235617-A1 Pharmaceutical dosage form for mucosal delivery SI, UGGT1, GYPA CYP3A4 67/4885LMNA 2639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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