Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21020435 | 0.85 | MEN1 (0.36) | MEN1KMT2ACYP2C19ALOX5LMNA | |
| SCHEMBL25068559 | 0.84 | ALOX5 (0.36) | ALOX5LMNANR1I2ADRA2ACYP2D6 | |
| SCHEMBL22059188 | 0.84 | ALOX5 (0.39) | MEN1KMT2ACYP2C19ALOX5LMNA | |
| SCHEMBL20649813 | 0.84 | MEN1 (0.35) | MEN1KMT2ACYP2C19ALOX5LMNA | |
| SCHEMBL23676613 | 0.84 | ALOX5 (0.36) | MEN1KMT2ACYP2C19ALOX5LMNA | |
| SCHEMBL24206311 | 0.84 | MEN1 (0.35) | MEN1KMT2ACYP2C19ALOX5LMNA | |
| SCHEMBL15746008 | 0.84 | MEN1 (0.35) | MEN1KMT2ACYP2C19ALOX5LMNA | |
| SCHEMBL14295583 | 0.83 | ALOX5 (0.37) | MEN1KMT2ACYP2C19ALOX5CYP2D6 | |
| SCHEMBL25061137 | 0.81 | TNKS (0.40) | MEN1KMT2ACYP2C19ALOX5LMNA | |
| SCHEMBL25061152 | 0.81 | ALOX5 (0.43) | MEN1KMT2ACYP2C19ALOX5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230059210-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| US-20230058635-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| WO-2020108899-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2020-06-04 | — | — | WO | disclosed |
| WO-2020109269-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2020-06-04 | — | — | WO | disclosed |