SCHEMBL15746008

SCHEMBL15746008

CC(C)(C)c1ccc(N(c2ccccc2)c2cccc3c2oc2ccccc23)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
CYP2C19 P33261 1/20 0.35
ALOX5 P09917 3/20 0.34
KEAP1 Q14145 1/20 0.34
NFE2L2 Q16236 1/20 0.34
PRSS1 P07477 1/20 0.34
PIK3CD O00329 1/20 0.33
PIK3CA P42336 1/20 0.33
PIK3CB P42338 1/20 0.33
PIK3CG P48736 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
THRB P10828 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TP53 P04637 2/20 0.32
LMNA P02545 2/20 0.32
NR1I2 O75469 1/20 0.32
ADRA2A P08913 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14295583 0.93 ALOX5 (0.37) MEN1KMT2ACYP2C19ALOX5PIK3CD
SCHEMBL25890837 0.92 KEAP1 (0.32) MEN1KMT2ACYP2C19ALOX5KEAP1
SCHEMBL27252693 0.91 ALOX5 (0.35) MEN1KMT2AALOX5SMN1; SMN2THRB
SCHEMBL25749540 0.91 CYP2C19 (0.34) MEN1KMT2ACYP2C19ALOX5MAPT
SCHEMBL14295291 0.89 ALOX5 (0.40) MEN1KMT2ACYP2C19ALOX5SMN1; SMN2
SCHEMBL15730662 0.87 ALOX5 (0.39) MEN1KMT2ACYP2C19ALOX5SMN1; SMN2
SCHEMBL15306316 0.87 ALOX5 (0.41) MEN1KMT2ACYP2C19ALOX5SMN1; SMN2
SCHEMBL23446819 0.86 AHR (0.34) MEN1KMT2ACYP2C19ALOX5AHR
SCHEMBL16710465 0.85 CYP2C19 (0.39) MEN1KMT2ACYP2C19ALOX5KEAP1
SCHEMBL12206548 0.85 KIF11 (0.33) MEN1KMT2ACYP2C19ALOX5SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190319194-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed
US-10381569-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US disclosed
US-9512136-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-12-06 US disclosed
US-20160149139-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-26 US disclosed
US-20140145149-A1 Organic Luminescent Compound With Delayed Fluorescence UNIVERSAL DISPLAY CORPORATION (US) 2014-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140145149-A1 Organic Luminescent Compound With Delayed Fluorescence OCIAD1, OCIAD2, MLYCD MEN1 4713/4885KMT2A 3646/4885CYP2C19 1940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.