Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2401504 | 0.86 | HTT (0.43) | HTTDNM1LMNA | |
| SCHEMBL21295572 | 0.83 | HTT (0.44) | HTTDNM1LMNA | |
| SCHEMBL15967789 | 0.80 | TSHR (0.36) | HTTTSHRDNM1ALDH1A1ADRB2 | |
| SCHEMBL28071184 | 0.80 | HTT (0.42) | HTTDNM1 | |
| SCHEMBL14975586 | 0.79 | TSHR (0.42) | HTTTSHRDNM1ALDH1A1ADRB2 | |
| SCHEMBL26925526 | 0.77 | SPHK1 (0.40) | HTTDNM1LMNA | |
| SCHEMBL22100679 | 0.76 | HTT (0.46) | HTTDNM1ALDH1A1CA1CA2 | |
| SCHEMBL8990536 | 0.76 | USP2 (0.43) | HTTDNM1ALDH1A1LMNA | |
| SCHEMBL28378452 | 0.75 | GPR84 (0.41) | HTTDNM1CA2LMNA | |
| SCHEMBL3237751 | 0.74 | ALDH1A1 (0.51) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020113209-A1 | PANTETHEINE DERIVATIVES AND USES THEREOF | COMET THERAPEUTICS, INC. (US) | 2020-06-04 | — | — | WO | disclosed |