Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 3/20 | 0.34 |
| ▸ | NOS2 | P35228 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28772079 | 0.86 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL1634401 | 0.83 | ALDH1A1 (0.42) | ALDH1A1NOS1NOS2NOS3SLC18A3 | |
| SCHEMBL4258705 | 0.78 | ALDH1A1 (0.35) | ALDH1A1 | |
| Biphenyl SCHEMBL9853201 | 0.73 | ALDH1A1 (0.73) | ALDH1A1NOS1NOS2SLC18A3 | |
| SCHEMBL6683741 | 0.73 | ALDH1A1 (0.89) | ALDH1A1NOS1NOS2SLC18A3 | |
| SCHEMBL231054 | 0.73 | ALDH1A1 (0.89) | ALDH1A1NOS1NOS2SLC18A3 | |
| SCHEMBL7738712 | 0.73 | ALDH1A1 (0.89) | ALDH1A1NOS1NOS2SLC18A3 | |
| SCHEMBL22284064 | 0.73 | ALDH1A1 (0.89) | ALDH1A1NOS1NOS2SLC18A3 | |
| SCHEMBL22284066 | 0.73 | ALDH1A1 (0.89) | ALDH1A1NOS1NOS2SLC18A3 | |
| SCHEMBL2999797 | 0.73 | ALDH1A1 (0.89) | ALDH1A1NOS1NOS2SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602932-B | Polyaldimines and curable polyurethane compositions | SIKA技术股份公司 | 2021-08-31 | — | — | CN | claimed |
| CN-1292308-C | Resin composition, process for producing resin composition, and method of forming resin film | SONY CHEMICALS CORP (JP) | 2006-12-27 | — | — | CN | claimed |
| CN-1503927-A | Resin composition, process for producing resin composition, and method of forming resin film | 索尼化学株式会社 | 2004-06-09 | — | — | CN | claimed |
| CN-110382587-B | Method for preparing curing agent of low-emission epoxy resin composition | SIKA技术股份公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-109563232-B | Two-component polyurethane adhesive with mechanical properties substantially unaffected by temperature and high strength | SIKA技术股份公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-108368233-B | Two-component polyurethane composition | SIKA技术股份公司 | 2022-02-08 | — | — | CN | disclosed |
| CN-108602932-B | Polyaldimines and curable polyurethane compositions | SIKA技术股份公司 | 2021-08-31 | — | — | CN | disclosed |
| CN-108368232-B | Polyurethane compositions with low plasticizer migration | SIKA技术股份公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-110799514-A | Silole and germacyclopentadiene fused ring photochromic compounds | 光学转变有限公司 | 2020-02-14 | — | — | CN | disclosed |
| US-7981883-B2 | Substituted spiro-compounds and the use thereof for producing medicaments | GRUENENTHAL GMBH (DE) | 2011-07-19 | — | — | US | disclosed |
| US-20090275628-A1 | Substituted Spiro-Compounds And The Use Thereof For Producing Medicaments | GRUENENTHAL GMBH (DE) | 2009-11-05 | — | — | US | disclosed |
| EP-1888542-A1 | SUBSTITUTED SPIRO-COMPOUNDS AND THE USE THEREOF FOR PRODUCING MEDICAMENTS | Grünenthal GmbH (DE) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006136245-A1 | SUBSTITUTED SPIRO-COMPOUNDS AND THE USE THEREOF FOR PRODUCING MEDICAMENTS | Grünenthal GmbH (DE) | 2006-12-28 | — | — | WO | disclosed |
| CN-1292308-C | Resin composition, process for producing resin composition, and method of forming resin film | SONY CHEMICALS CORP (JP) | 2006-12-27 | — | — | CN | disclosed |
| CN-1503927-A | Resin composition, process for producing resin composition, and method of forming resin film | 索尼化学株式会社 | 2004-06-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275628-A1 | Substituted Spiro-Compounds And The Use Thereof For Producing Medicaments | REN, PKD1, PKD2 | ALDH1A1 218/4885NOS1 2408/4885NOS2 2043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.